Poly(d,l-lacticacid) electrospun fibers with tunable surface nanotopography for modulatin gdru grelease profiles
文献类型:期刊论文
作者 | Shuai Wu; Jun Wu; Jianhui Yue; MichaelK.T. To; Haobo Pan; William W.Lu; XiaoliZhao |
刊名 | Materials Letters
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出版日期 | 2015 |
英文摘要 | Poly (d,l-lacticacid) microfibers with tunable nanoporous structure in the superficial layer were fabricated by electrospinning. The density and size of nanopores were controlled by the components of electrospun solvent, which were attributed to the competition between phasese parathion and solvent evaporation. The nanotopography influenced the mechanical strength, hydrophobicity, and degradation rate of the microfibers. Moreimportantly, it increased the cumulative drug release. The rifampicin loading efficiency was mainly dependent on the drug loading method. This study provided a novel technique to modulate the drug release profiles of PDLLA microfibers by the surface nanotopography. |
收录类别 | SCI |
原文出处 | http://www.sciencedirect.com/science/article/pii/S0167577X15305772 |
语种 | 英语 |
源URL | [http://ir.siat.ac.cn:8080/handle/172644/7389] ![]() |
专题 | 深圳先进技术研究院_医药所 |
作者单位 | Materials Letters |
推荐引用方式 GB/T 7714 | Shuai Wu,Jun Wu,Jianhui Yue,et al. Poly(d,l-lacticacid) electrospun fibers with tunable surface nanotopography for modulatin gdru grelease profiles[J]. Materials Letters,2015. |
APA | Shuai Wu.,Jun Wu.,Jianhui Yue.,MichaelK.T. To.,Haobo Pan.,...&XiaoliZhao.(2015).Poly(d,l-lacticacid) electrospun fibers with tunable surface nanotopography for modulatin gdru grelease profiles.Materials Letters. |
MLA | Shuai Wu,et al."Poly(d,l-lacticacid) electrospun fibers with tunable surface nanotopography for modulatin gdru grelease profiles".Materials Letters (2015). |
入库方式: OAI收割
来源:深圳先进技术研究院
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