Oxygen Nanocarrier for Combined Cancer Therapy: Oxygen-Boosted ATP-Responsive Chemotherapy with Amplified ROS Lethality
文献类型：期刊论文
| 作者 | P.F. Zhao; M.B. Zheng; Z.Y. Luo; X.J. Fan; Z.H. Sheng; P. Gong; Z. Chen; B.Z. Zhang; D.P. Ni; Y.F. Ma |
| 刊名 | Advanced Healthcare Materials
 |
| 出版日期 | 2016 |
| 英文摘要 | Oxygen nanocarrier (A/D-ONC) with a polymeric core entrapping hemoglobin and a cationic lipid shell absorbing a DOX-intercalating DNA duplex is developed. After endocytosis oxygenated A/D-ONC donates O2 to cancer cells that acts therapeutically by: (1) increasing intracellular ATP content that promotes DOX release, thereby converting ATP to the trigger of detrimental chemotherapy; (2) by synchronously increasing the ROS amount to amplify the lethality to cancer cells. |
| 收录类别 | SCI |
| 原文出处 | http://europepmc.org/abstract/med/27253453 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/10691]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | Advanced Healthcare Materials |
| 推荐引用方式 GB/T 7714 | P.F. Zhao,M.B. Zheng,Z.Y. Luo,et al. Oxygen Nanocarrier for Combined Cancer Therapy: Oxygen-Boosted ATP-Responsive Chemotherapy with Amplified ROS Lethality[J]. Advanced Healthcare Materials,2016. |
| APA | P.F. Zhao.,M.B. Zheng.,Z.Y. Luo.,X.J. Fan.,Z.H. Sheng.,...&L.T. Cai.(2016).Oxygen Nanocarrier for Combined Cancer Therapy: Oxygen-Boosted ATP-Responsive Chemotherapy with Amplified ROS Lethality.Advanced Healthcare Materials. |
| MLA | P.F. Zhao,et al."Oxygen Nanocarrier for Combined Cancer Therapy: Oxygen-Boosted ATP-Responsive Chemotherapy with Amplified ROS Lethality".Advanced Healthcare Materials (2016). |
入库方式： OAI收割
来源：深圳先进技术研究院
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