Stretching-induced nanostructures on shape memory polyurethane films and their regulation to osteoblasts morphology
文献类型：期刊论文
| 作者 | Juan Xing; Yufei Ma; Manping Lin; Yuanliang Wang; Haobo Pan; Changshun Ruan; Yanfeng Luo |
| 刊名 | COLLOIDS AND SURFACES B-BIOINTERFACES
 |
| 出版日期 | 2016 |
| 英文摘要 | Programming such as stretching, compression and bending is indispensible to endow polyurethanes with shape memory effects. Despite extensive investigations on the contributions of programming processes to the shape memory effects of polyurethane, less attention has been paid to thenanostructures of shape memory polyurethanes surface during the programming process. Here we found that stretching could induce the reassembly of hard domains and thereby change the nanostructures on the film surfaces with dependence on the stretching ratios (0%, 50%, 100%, and 200%). In as-castpolyurethane films, hard segments sequentially assembled into nano-scale hard domains, round or fibrillar islands, and fibrillar apophyses. Upon stretching, the islands packed along the stretching axis to form reoriented fibrillar apophyses along the stretching direction. Stretching only changed the chemical patterns on polyurethane films without significantly altering surface roughness, with the primary composition of fibrillar apophyses being hydrophilic hard domains. Further analysis of osteoblasts morphology revealed that the focal adhesion formation and osteoblasts orientation were in accordance with the chemical patterns of the underlying stretched films, which corroborates the vital roles of stretching-induced nanostructures in regulating osteoblastsmorphology. These novel findings suggest that programming might hold great potential for patterning polyurethane surfaces so as to direct cellular behavior. In addition, this work lays groundwork for guiding the programming of shape memory polyurethanes to produce appropriate nanostructures for predetermined medical applications. |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1016/j.colsurfb.2016.06.044 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/10761]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | COLLOIDS AND SURFACES B-BIOINTERFACES |
| 推荐引用方式 GB/T 7714 | Juan Xing,Yufei Ma,Manping Lin,et al. Stretching-induced nanostructures on shape memory polyurethane films and their regulation to osteoblasts morphology[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2016. |
| APA | Juan Xing.,Yufei Ma.,Manping Lin.,Yuanliang Wang.,Haobo Pan.,...&Yanfeng Luo.(2016).Stretching-induced nanostructures on shape memory polyurethane films and their regulation to osteoblasts morphology.COLLOIDS AND SURFACES B-BIOINTERFACES. |
| MLA | Juan Xing,et al."Stretching-induced nanostructures on shape memory polyurethane films and their regulation to osteoblasts morphology".COLLOIDS AND SURFACES B-BIOINTERFACES (2016). |
入库方式： OAI收割
来源：深圳先进技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。