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In vitro study on an antibacterial Ti-5Cu alloy for medical application

文献类型:期刊论文

作者Ma, Zheng; Li, Mei; Liu, Rui; Ren, Ling; Zhang, Yu; Pan, Haobo; Zhao, Ying; Yang, Ke
刊名JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
出版日期2016
英文摘要Health of human beings is subjected to severe threats from the spread of harmful bacteria and the implantassociated infection remains a serious problem in clinic. In this study, a copper-bearing antibacterial titanium alloy, Ti–5Cu, has been developed for dental and orthopedic implant applications. The microstructure, mechanical property, electrochemical corrosion behavior, in vitro antibacterial performance, cytocompatibility and hemocompatibility of the alloy are systematically investigated. The results reveal that the Ti–5Cu alloy which consists of a-phase matrix and intermetallic compound Ti2Cu not only possesses strong antibacterial activity against both E. coli and S. aureus, but also exhibits better mechanical properties than the commercial pure titanium. It is confirmed that the release of trace amount of Cu ions from the alloy plays an important role in killing bacteria. In spite of the ion release, Ti–5Cu alloy still reveals excellent corrosion resistance. Moreover, good cytocompatibility and superior hemocompatibility make Ti–5Cu alloy to be a potential solution that could prevent the peri-implant infection in dental and orthopaedic applications.
收录类别SCI
原文出处http://link.springer.com/article/10.1007%2Fs10856-016-5698-1
语种英语
源URL[http://ir.siat.ac.cn:8080/handle/172644/10765]  
专题深圳先进技术研究院_医药所
作者单位JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
推荐引用方式
GB/T 7714
Ma, Zheng,Li, Mei,Liu, Rui,et al. In vitro study on an antibacterial Ti-5Cu alloy for medical application[J]. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE,2016.
APA Ma, Zheng.,Li, Mei.,Liu, Rui.,Ren, Ling.,Zhang, Yu.,...&Yang, Ke.(2016).In vitro study on an antibacterial Ti-5Cu alloy for medical application.JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE.
MLA Ma, Zheng,et al."In vitro study on an antibacterial Ti-5Cu alloy for medical application".JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE (2016).

入库方式: OAI收割

来源:深圳先进技术研究院

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