Bioinspired titanium coatings: self-assembly of collagen-alginate films for enhanced osseointegration
文献类型：期刊论文
| 作者 | Gregurec, Danijela; Wang, Guocheng; Pires, Ricardo H.; Kosutic, Marija; Luedtke, Tanja; Delcea, Mihaela; Enrique Moya, Sergio |
| 刊名 | JOURNAL OF MATERIALS CHEMISTRY B
 |
| 出版日期 | 2016 |
| 英文摘要 | Achieving long term osseointegration is fundamental to the development of successful bone implants. A key aspect for improving long term osseointegration on titania surfaces is to gain control of nano- and microscale features. The so called biological approach is applied here to modify the surface of titania by coating it with a self-assembled and chemically crosslinked biopolymer film made of alginate and collagen. The biofilm coated titania closely mimics the bone extracellular matrix in bio-morphology and mechanical properties. Biofilms are prepared using the layer by layer technique combined with carbodiimide chemistry to achieve a stable and compact structure. Alginate-collagen coatings display fibrillar morphology with an apparent fiber diameter of similar to 50 nm and lengths ranging from a few hundred nanometers to similar to 3 mm, mimicking therefore the extracellular matrix of the bone in fiber length and extent. Osteoblast MC3T3-E1 cells showed enhanced adhesion on the coated surface compared to the bare titania and a superior biological activity of the alginate-terminated coating that interfaces the cells in biological fluids. |
| 收录类别 | SCI |
| 原文出处 | http://pubs.rsc.org/en/content/articlehtml/2016/tb/c6tb00204h |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/10770]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | JOURNAL OF MATERIALS CHEMISTRY B |
| 推荐引用方式 GB/T 7714 | Gregurec, Danijela,Wang, Guocheng,Pires, Ricardo H.,et al. Bioinspired titanium coatings: self-assembly of collagen-alginate films for enhanced osseointegration[J]. JOURNAL OF MATERIALS CHEMISTRY B,2016. |
| APA | Gregurec, Danijela.,Wang, Guocheng.,Pires, Ricardo H..,Kosutic, Marija.,Luedtke, Tanja.,...&Enrique Moya, Sergio.(2016).Bioinspired titanium coatings: self-assembly of collagen-alginate films for enhanced osseointegration.JOURNAL OF MATERIALS CHEMISTRY B. |
| MLA | Gregurec, Danijela,et al."Bioinspired titanium coatings: self-assembly of collagen-alginate films for enhanced osseointegration".JOURNAL OF MATERIALS CHEMISTRY B (2016). |
入库方式： OAI收割
来源：深圳先进技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。