Dextran Based Calcium Phosphate Nanoparticles for Dual-modal Imaging Guided Photothermal Therapy
文献类型：会议论文
| 作者 | Peng Liu; Zexuan Ding; Huqiang Yi; Lintao Cai |
| 出版日期 | 2015 |
| 会议名称 | ChinaNanomedicine 2015 |
| 会议地点 | Hangzhou, China |
| 英文摘要 | Photothermal therapy (PTT) is an appealing strategy for tumor treatment. To achieve high therapy efficiency, the location of tumor must be precisely identified before therapy. Dual-modal imaging guided photothermal therapy (PTT) is utlized as an effective treatment for tumor owing to its accurate imaging to tumor sites. Herein, we fabricated a dextran coated ICG/Gd3+ dual-doped calcium phosphate nanoparticle system. The obtained nanoparticles with an average diameter around 150 nm exhibit high ICG encapsulation efficiency (DLC: 10.9%) and good stability. Furthermore, it was proved that the obtained nanoparticles could serve as a contrast agent to NIR imaging and enhance MRI in vitro. In addition, the in vitro therapeutic examinations showed that this system was an effective agent for photothermal therapy of cancer. |
| 收录类别 | 其他 |
| 语种 | 英语 |
| WOS记录号 | WOS:000373923400164 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/7444]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | 2015 |
| 推荐引用方式 GB/T 7714 | Peng Liu,Zexuan Ding,Huqiang Yi,et al. Dextran Based Calcium Phosphate Nanoparticles for Dual-modal Imaging Guided Photothermal Therapy[C]. 见:ChinaNanomedicine 2015. Hangzhou, China. |
入库方式： OAI收割
来源：深圳先进技术研究院
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