Alendronate-modified liposome for bone targeting gene delivery regulating mesenchymal stem cell migration
文献类型：会议论文
| 作者 | Chuping Zheng; Haobo Pan; Xiaoli Zhao |
| 出版日期 | 2016 |
| 会议名称 | International Combined meeting of Orthopaedic Research Societies |
| 会议地点 | 陕西西安 |
| 英文摘要 | Aging is usually related to an increase in metabolic skeletal disorders such as osteoporosis and bone metastases, accompanied with the decrease in mesenchymal stem cells (MSCs) number.1 For bone regeneration, directing MSCs toward the bone surface is a key step for further osteogenic differentiation.2 Stromal cell-derived factor-1 (SDF-1) has been reported with the effect in inducing MSC migration.3 Construction of the bone targeted gene delivery system would be a promising way to locally express SDF-1 on bone surface for attracting MSC migration and differentiation. This study aimed to develop bone targeting liposome by alendronate (Aln) modification for modulating MSC migration. |
| 收录类别 | 其他 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/10801]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 作者单位 | 2016 |
| 推荐引用方式 GB/T 7714 | Chuping Zheng,Haobo Pan,Xiaoli Zhao. Alendronate-modified liposome for bone targeting gene delivery regulating mesenchymal stem cell migration[C]. 见:International Combined meeting of Orthopaedic Research Societies. 陕西西安. |
入库方式： OAI收割
来源：深圳先进技术研究院
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