Near-Infrared (NIR)-Absorbing Conjugated Polymer Dots as Highly Effective Photothermal Materials for In Vivo Cancer Therapy
文献类型：期刊论文
| 作者 | Li, Shengliang1; Wang, Xiaoyu1; Hu, Rong1; Chen, Hui1; Li, Meng1; Wang, Jianwu1; Wang, Yunxia1; Liu, Libing1; Lv, Fengting1; Liang, Xing-Jie2 |
| 刊名 | CHEMISTRY OF MATERIALS
 |
| 出版日期 | 2016-12-13 |
| 卷号 | 28期号:23页码:8669-8675 |
| 英文摘要 | Photothermal therapy (PTT) holds great promise for noninvasive cancer treatment. To fulfill this goal, highly effective and low-risk photothermal agents have been intensively explored. Here, we present a new PTT material based on conjugated polymer dots (Pdots) that exhibit strong near-infrared (NIR) absorption and high photostability. The Pdots result in a thermal response upon illumination with a NIR laser, leading to a high photothermal conversion efficiency of 65%. Thus, the photothermal ablation of cancer cells using the Pdots both in vitro and in vivo can be achieved, highlighting the potential of Pdots as a nanoplatform for clinical therapy. They also open up a new avenue to develop new photothermal therapeutic materials. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/36517]  |
| 专题 | 化学研究所_有机固体实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Natl Ctr Nanosci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, Ctr Excellence Nanosci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Shengliang,Wang, Xiaoyu,Hu, Rong,et al. Near-Infrared (NIR)-Absorbing Conjugated Polymer Dots as Highly Effective Photothermal Materials for In Vivo Cancer Therapy[J]. CHEMISTRY OF MATERIALS,2016,28(23):8669-8675. |
| APA | Li, Shengliang.,Wang, Xiaoyu.,Hu, Rong.,Chen, Hui.,Li, Meng.,...&Wang, Shu.(2016).Near-Infrared (NIR)-Absorbing Conjugated Polymer Dots as Highly Effective Photothermal Materials for In Vivo Cancer Therapy.CHEMISTRY OF MATERIALS,28(23),8669-8675. |
| MLA | Li, Shengliang,et al."Near-Infrared (NIR)-Absorbing Conjugated Polymer Dots as Highly Effective Photothermal Materials for In Vivo Cancer Therapy".CHEMISTRY OF MATERIALS 28.23(2016):8669-8675. |
入库方式： OAI收割
来源：化学研究所
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