DNA methylation and hypertension: emerging evidence and challenges
文献类型：期刊论文
| 作者 | Han LY1; Liu YF1; He YH[*]5; Duan SW2; Perry B3; Li W[*]4 |
| 刊名 | Briefings in Functional Genomics
 |
| 出版日期 | 2016 |
| 卷号 | 15期号:6页码:460-469 |
| 关键词 | DNA methylation hypertension epigenetics gene expression gene transcription environmental factor |
| 通讯作者 | ssynfm@163.com ; heyonghan@mail.kiz.ac.cn |
| 英文摘要 | Hypertension is a multifactorial disease influenced by an interaction of environmental and genetic factors. The exact molecular mechanism of hypertension remains unknown. Aberrant DNA methylation is the most well-defined epigenetic modification that regulates gene transcription. However, studies on the association between DNA methylation and hypertension are still in their infancy. This review summarizes the latest evidence and challenges regarding the role of DNA methylation on hypertension. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by grants from the National Basic Research Program of China (2013CB530802 to Y.H.H.), Yunnan Province (2013FB069 to Y.H.H.), the Natural Science Foundation of China (81500670 to Y.H.H., 81402745 to L.Y.H.), K. C. Wong Magna Fund through Ningbo University and the China Postdoctoral Science Foundation funded pro- ject (156458 to L.Y.H.). |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/10960]  |
| 专题 | 昆明动物研究所_分子人类学 |
| 作者单位 | 1.Medical School of Ningbo University, Zhejiang Provincial Key Laboratory of Pathophysiology 2.Medical School of Ningbo University 3.OmniActive Health Technologies (Canada) Ltd 4.Third People’s Hospital of Yunnan Province 5.Kunming Institute of Zoology, Chinese Academy of Sciences |
| 推荐引用方式 GB/T 7714 | Han LY,Liu YF,He YH[*],et al. DNA methylation and hypertension: emerging evidence and challenges[J]. Briefings in Functional Genomics,2016,15(6):460-469. |
| APA | Han LY,Liu YF,He YH[*],Duan SW,Perry B,&Li W[*].(2016).DNA methylation and hypertension: emerging evidence and challenges.Briefings in Functional Genomics,15(6),460-469. |
| MLA | Han LY,et al."DNA methylation and hypertension: emerging evidence and challenges".Briefings in Functional Genomics 15.6(2016):460-469. |
入库方式： OAI收割
来源：昆明动物研究所
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