Monomer composition of chitooligosaccharides obtained by different degradation methods and their effects on immunomodulatory activities
文献类型：期刊论文
| 作者 | Xing, Ronge1,2 ; Liu, Yongliang1,2,3; Li, Kecheng1,2; Yu, Huahua1,2; Liu, Song1,2; Yang, Yue1,2; Chen, Xiaolin1,2; Li, Pengcheng1,2
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| 刊名 | CARBOHYDRATE POLYMERS
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| 出版日期 | 2017-02-10 |
| 卷号 | 157页码:1288-1297 |
| 关键词 | Chitooligosaccharide Degradation methods Monomer composition Immunomodulatory activities Chitosan |
| 英文摘要 | Three kinds of chitooligosaccharides were prepared using traditional (ZCOS), microwave irradiation (WCOS), and enzymatic hydrolysis (YCOS), and their monomer compositions and in vitro and in vivo immunomodulatory activities were determined. ZCOS was mainly comprised of disaccharides and trisaccharides; WCOS was mainly comprised of disaccharides to hexasaccharides with or without acetyl groups; and YCOS was mainly comprised of trisaccharides to pentasaccharides without acetyl groups. Differences in monomer composition and acetyl groups affected their immunomodulatory activities. Chitooligosaccharides degraded by different methods: all significantly stimulated the immune system by acting through cellular and humoral immunities. WCOS, obtained by microwave irradiation, had the best immunomodulatory activity. It significantly increased the spleen index and significantly stimulated delayed-type hypersensitivity compared the other two chitooligosaccharides. These activities might have been the result of the hexamer and acetyl groups of WCOS. (C) 2016 Published by Elsevier Ltd. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000391896800143 |
| 版本 | 出版稿 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/136279]  |
| 专题 | 海洋研究所_海洋生物技术研发中心 海洋研究所_海洋环境工程技术研究发展中心 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Beijing 100864, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Beijing 100864, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xing, Ronge,Liu, Yongliang,Li, Kecheng,et al. Monomer composition of chitooligosaccharides obtained by different degradation methods and their effects on immunomodulatory activities[J]. CARBOHYDRATE POLYMERS,2017,157:1288-1297. |
| APA | Xing, Ronge.,Liu, Yongliang.,Li, Kecheng.,Yu, Huahua.,Liu, Song.,...&Li, Pengcheng.(2017).Monomer composition of chitooligosaccharides obtained by different degradation methods and their effects on immunomodulatory activities.CARBOHYDRATE POLYMERS,157,1288-1297. |
| MLA | Xing, Ronge,et al."Monomer composition of chitooligosaccharides obtained by different degradation methods and their effects on immunomodulatory activities".CARBOHYDRATE POLYMERS 157(2017):1288-1297. |
入库方式： OAI收割
来源：海洋研究所
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