Renoprotective effect of low-molecular-weight sulfated polysaccharide from the seaweed Laminaria japonica on glycerol-induced acute kidney injury in rats
文献类型：期刊论文
| 作者 | Li, Xinpeng1,3 ; Wang, Jing1,2; Zhang, Hong1,2; Zhang, Quanbin1,2
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| 刊名 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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| 出版日期 | 2017-02-01 |
| 卷号 | 95页码:132-137 |
| 关键词 | Acute kidney injury Low-molecular-weight sulfated polysaccharide Renal protective effect |
| 英文摘要 | We investigated the renal protective effect of low-molecular-weight sulfated polysaccharide (LMWSP) fractions extracted from Laminaria japonica on glycerol-induced acute kidney injury (AKI) in rats. Glycerol treatment significantly increased serum creatinine (SCr) and blood urea nitrogen (BUN) levels. Intraperitoneal injection of LMWSP fractions markedly decreased SCr and BUN levels and reduced renal swelling. The fraction of 1.0 M NaCl displayed the best renal protective effect of all fractions in attenuating AKI and maintaining blood glucose. (C) 2016 Elsevier B.V. All rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000392903000018 |
| 版本 | 出版稿 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/136303]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 海洋研究所_海洋生物技术研发中心 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Beijing 100864, Peoples R China 2.Qjngdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Xinpeng,Wang, Jing,Zhang, Hong,et al. Renoprotective effect of low-molecular-weight sulfated polysaccharide from the seaweed Laminaria japonica on glycerol-induced acute kidney injury in rats[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2017,95:132-137. |
| APA | Li, Xinpeng,Wang, Jing,Zhang, Hong,&Zhang, Quanbin.(2017).Renoprotective effect of low-molecular-weight sulfated polysaccharide from the seaweed Laminaria japonica on glycerol-induced acute kidney injury in rats.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,95,132-137. |
| MLA | Li, Xinpeng,et al."Renoprotective effect of low-molecular-weight sulfated polysaccharide from the seaweed Laminaria japonica on glycerol-induced acute kidney injury in rats".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 95(2017):132-137. |
入库方式： OAI收割
来源：海洋研究所
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