BMSCs-laden gelatin/sodium alginate/carboxymethyl chitosan hydrogel for 3D bioprinting
文献类型：期刊论文
| 作者 | Huang, Jie(黄洁); Fu, Han(付寒); Wang, Zhiying(王芷莹); Meng, Qingyuan; Liu, Sumei; Wang, Heran; Zheng, Xiongfei; Dai, Jianwu(戴建武); Zhang, Zhijun(张智军) |
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2016 |
| 卷号 | 6期号:110 |
| 通讯作者 | Dai, JW(戴建武) ; Zhang, ZJ(张智军) |
| 英文摘要 | Three-dimensional (3D) bioprinting technology offers the possibility to deliver, in a defined and organized manner, scaffolding materials and living cells, and therefore holds much promise for tissue engineering and regenerative medicine. In this work, we explored the possibility of gelatin/sodium alginate/carboxymethyl chitosan (Gel/SA/CMCS) hydrogel combining with bone mesenchymal stem cells (BMSCs) for 3D bioprinting. Compared to the commonly used 3D bioprinting materials such as gelatin/sodium alginate (Gel/SA) hydrogel, the Gel/SA/CMCS hydrogel we developed shows excellent equilibrium water content, good mechanical properties, antibacterial activity, and a slow degradation rate. With this kind of material, we generated a scaffold with homogenous cell distribution. Cell viability after 3D printing showed that over 85% of the printed cells were viable at 0 and 2 days of culturing. Our work demonstrates the feasibility of mixing Gel/SA/CMCS hydrogel with stem cells for 3D bioprinting. |
| 关键词[WOS] | MESENCHYMAL STEM-CELLS ; ENGINEERED CARTILAGE CONSTRUCTS ; OSTEOGENIC DIFFERENTIATION ; VALVE CONDUITS ; TISSUE ; ALGINATE ; ORGANIZATION ; FABRICATION ; SCAFFOLDS ; CULTURE |
| 收录类别 | SCI ; EI |
| 语种 | 英语 |
| WOS记录号 | WOS:000389342800036 |
| 源URL | [http://ir.sinano.ac.cn/handle/332007/4848]  |
| 专题 | 苏州纳米技术与纳米仿生研究所_纳米生物医学与安全研究部_戴建武团队 |
| 推荐引用方式 GB/T 7714 | Huang, Jie,Fu, Han,Wang, Zhiying,et al. BMSCs-laden gelatin/sodium alginate/carboxymethyl chitosan hydrogel for 3D bioprinting[J]. RSC ADVANCES,2016,6(110). |
| APA | Huang, Jie.,Fu, Han.,Wang, Zhiying.,Meng, Qingyuan.,Liu, Sumei.,...&Zhang, Zhijun.(2016).BMSCs-laden gelatin/sodium alginate/carboxymethyl chitosan hydrogel for 3D bioprinting.RSC ADVANCES,6(110). |
| MLA | Huang, Jie,et al."BMSCs-laden gelatin/sodium alginate/carboxymethyl chitosan hydrogel for 3D bioprinting".RSC ADVANCES 6.110(2016). |
入库方式： OAI收割
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。