Logic gates based on G-quadruplexes: principles and sensor applications
文献类型：期刊论文
| 作者 | Guo, YH; Yao, WR; Xie, YF; Zhou, XD; Hu, JM; Pei, RJ(裴仁军) |
| 刊名 | MICROCHIMICA ACTA
 |
| 出版日期 | 2016 |
| 卷号 | 183期号:1 |
| 通讯作者 | Hu, JM |
| 英文摘要 | This review (with 139 refs.) gives a fundamental introduction into the sensors and logic gates based on G-quadruplexes (G4s). G4 characterizes vibrant binding activities and topology diversity, which contribute to the multiple signal output modes (including labeled moieties based on distance changes, label-free outputs by employing fluorescent ligands, G4/hemin DNAzyme with catalyzing activity and colorimetric readout using gold nanoparticles) and versatile design strategies (including target-induced G4 formation/disruption, liberation of blocked G4, split G4 probes, polymerase-assisted amplification and G4/hemin enrichment on sensor surface) of G4s-based methods. Following two important trends in logic gates (application of intelligent detection schemes and logic circuit constructions), specific sections review logic sensors and logic circuits based on G4s with several representative examples. We close this review with conclusions and give a perspective that employment of DNA technologies (such as aptamers, DNA junctions/origami, toehold-mediated strand displacement, enzyme-assisted amplification, metal ion-dependent DNAzymes) and various nanomaterials in G4s-based methods results in quite a large potential in terms of logic detection and construction of logic circuits. |
| 关键词[WOS] | DNA STRAND DISPLACEMENT ; PARALLEL G-QUADRUPLEX ; UNMODIFIED GOLD NANOPARTICLES ; ROLLING CIRCLE AMPLIFICATION ; AGGREGATION-INDUCED EMISSION ; INPUT-DEPENDENT INDUCTION ; TELOMERIC G-QUADRUPLEX ; CDSE/ZNS QUANTUM DOTS ; LABEL-FREE DETECTION ; MERCURY ION HG2+ |
| 收录类别 | SCI ; EI |
| 语种 | 英语 |
| WOS记录号 | WOS:000367692900002 |
| 源URL | [http://ir.sinano.ac.cn/handle/332007/4873]  |
| 专题 | 苏州纳米技术与纳米仿生研究所_纳米生物医学与安全研究部_裴仁军团队 |
| 推荐引用方式 GB/T 7714 | Guo, YH,Yao, WR,Xie, YF,et al. Logic gates based on G-quadruplexes: principles and sensor applications[J]. MICROCHIMICA ACTA,2016,183(1). |
| APA | Guo, YH,Yao, WR,Xie, YF,Zhou, XD,Hu, JM,&Pei, RJ.(2016).Logic gates based on G-quadruplexes: principles and sensor applications.MICROCHIMICA ACTA,183(1). |
| MLA | Guo, YH,et al."Logic gates based on G-quadruplexes: principles and sensor applications".MICROCHIMICA ACTA 183.1(2016). |
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