The development of a light-up red-emitting fluorescent probe based on a G-quadruplex specific cyanine dye
文献类型：期刊论文
| 作者 | Chen, X(陈星); Wang, J(王金娥); Jiang, GM(江桂梅); Zu, GY(祖广月); Liu, M(刘敏); Zhou, L(周璐); Pei, RJ(裴仁军) |
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2016 |
| 卷号 | 6期号:74 |
| 通讯作者 | Pei, RJ(裴仁军) |
| 英文摘要 | A cyanine dye-dimethylindole red containing an extending polymethine chain, a sterically bulky dimethylindole heterocycle and an anionic propylsulfonate substituent on the quinoline ring was found to behave as a high specific light-up G-quadruplex probe in the red-emitting region above 650 nm, especially for parallel G-quadruplex c-myc. The 10 to 70-fold enhancement in the fluorescence quantum yield of dimethylindole red when incubating with G-quadruplexes may benefit more accurate definition of the distribution of G-quadruplexes across the genome. |
| 关键词[WOS] | PARALLEL G-QUADRUPLEXES ; NAPHTHALENE DIIMIDE DYAD ; SWITCH-ON PROBE ; DISPLACEMENT ASSAY ; NUCLEIC-ACIDS ; DNA ; PROMOTER ; TRANSCRIPTION ; SELECTIVITY ; AFFINITY |
| 收录类别 | SCI ; EI |
| 语种 | 英语 |
| WOS记录号 | WOS:000381512800057 |
| 源URL | [http://ir.sinano.ac.cn/handle/332007/4911]  |
| 专题 | 苏州纳米技术与纳米仿生研究所_纳米生物医学与安全研究部_裴仁军团队 |
| 推荐引用方式 GB/T 7714 | Chen, X,Wang, J,Jiang, GM,et al. The development of a light-up red-emitting fluorescent probe based on a G-quadruplex specific cyanine dye[J]. RSC ADVANCES,2016,6(74). |
| APA | Chen, X.,Wang, J.,Jiang, GM.,Zu, GY.,Liu, M.,...&Pei, RJ.(2016).The development of a light-up red-emitting fluorescent probe based on a G-quadruplex specific cyanine dye.RSC ADVANCES,6(74). |
| MLA | Chen, X,et al."The development of a light-up red-emitting fluorescent probe based on a G-quadruplex specific cyanine dye".RSC ADVANCES 6.74(2016). |
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