Coassembly of Tobacco Mosaic Virus Coat Proteins into Nanotubes with Uniform Length and Improved Physical Stability
文献类型：期刊论文
| 作者 | Zhou, K(周堃); Eiben, S; Wang, QB(王强斌) |
| 刊名 | ACS APPLIED MATERIALS & INTERFACES
 |
| 出版日期 | 2016 |
| 卷号 | 8期号:21页码:13192-13196 |
| 关键词 | chimerical scaffold coassembly disulfide bond length-controllability physical stabilization tobacco mosaic virus |
| 通讯作者 | Wang, QB(王强斌) |
| 英文摘要 | Using tobacco mosaic virus coat proteins (TMVcp) from both sources of the plant and bacterial expression systems as building blocks, we demonstrate here a coassembly strategy of TMV nanotubes in the presence of RNA. Specifically, plant-expressed cp (cp(p)) efficiently dominates the genomic RNA encapsidation to determine the length of assembled TMV nanotubes, whereas the incorporated Escherichia coli-expressed cp (cp(ec)) improves the physical stability of TMV nanotubes by introducing disulfide bonds between the interfaces of subunits. We expect this coassembly strategy can be expanded to other virus nanomaterials to obtain desired properties based on rationally designed protein-RNA and protein-protein interfacial interactions. |
| 关键词[WOS] | NANOSTRUCTURES ; NANORODS ; RNA ; BIOTECHNOLOGY ; NANOPARTICLES ; NANOMATERIALS ; INTEGRATION ; PARTICLES ; PEPTIDES ; DISPLAY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000377150400003 |
| 源URL | [http://ir.sinano.ac.cn/handle/332007/4533]  |
| 专题 | 苏州纳米技术与纳米仿生研究所_纳米生物医学与安全研究部_王强斌团队 |
| 推荐引用方式 GB/T 7714 | Zhou, K,Eiben, S,Wang, QB. Coassembly of Tobacco Mosaic Virus Coat Proteins into Nanotubes with Uniform Length and Improved Physical Stability[J]. ACS APPLIED MATERIALS & INTERFACES,2016,8(21):13192-13196. |
| APA | Zhou, K,Eiben, S,&Wang, QB.(2016).Coassembly of Tobacco Mosaic Virus Coat Proteins into Nanotubes with Uniform Length and Improved Physical Stability.ACS APPLIED MATERIALS & INTERFACES,8(21),13192-13196. |
| MLA | Zhou, K,et al."Coassembly of Tobacco Mosaic Virus Coat Proteins into Nanotubes with Uniform Length and Improved Physical Stability".ACS APPLIED MATERIALS & INTERFACES 8.21(2016):13192-13196. |
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