Facile synthesis of magnetic-plasmonic nanocomposites as T (1) MRI contrast enhancing and photothermal therapeutic agents
文献类型：期刊论文
| 作者 | Yang, ZZ(杨钟贞); Ding, XG(丁显光); Jiang, J(姜江) |
| 刊名 | NANO RESEARCH
 |
| 出版日期 | 2016 |
| 卷号 | 9期号:3 |
| 通讯作者 | Jiang, J(姜江) |
| 英文摘要 | Nanocomposites combining magnetic and plasmonic components have received widespread attention in recent years due to their potential applications in biomedical research. Herein, we describe a facile method for growing small iron oxide nanoparticles on various plasmonic core materials with different shapes and surfaces by utilizing a polypyrrole interlayer. By focusing on Au nanorod@polypyrrole@iron oxide (Au NR@PPy@Fe (x) O) nanocomposites, we show that these systems exhibit a low r (2)/r (1) ratio of 4.8, making them efficient T (1) positive contrast-enhancing agents for magnetic resonance imaging (MRI). Moreover, we show that the nanocomposites are excellent photothermal agents in the second near infrared region, with high photothermal conversion efficiency, reaching up to 46%. In addition, the Au NR@PPy@Fe (x) O nanocomposites show very low cytotoxicity. In summary, the present results highlight the great potential of the synthetic method and the nanocomposites developed in this study for T (1) MRI and/or infrared thermal imaging-guided photothermal cancer therapeutic applications. |
| 关键词[WOS] | IN-VIVO ; POLYPYRROLE NANOPARTICLES ; OXIDE NANOPARTICLES ; CANCER-THERAPY ; INORGANIC NANOPARTICLES ; SHELL NANOPARTICLES ; GOLD NANOPARTICLES ; RESONANCE ; CELLS ; GADOLINIUM |
| 收录类别 | SCI ; EI |
| 语种 | 英语 |
| WOS记录号 | WOS:000371797000020 |
| 源URL | [http://ir.sinano.ac.cn/handle/332007/4585]  |
| 专题 | 苏州纳米技术与纳米仿生研究所_纳米研究国际实验室_姜江团队 |
| 推荐引用方式 GB/T 7714 | Yang, ZZ,Ding, XG,Jiang, J. Facile synthesis of magnetic-plasmonic nanocomposites as T (1) MRI contrast enhancing and photothermal therapeutic agents[J]. NANO RESEARCH,2016,9(3). |
| APA | Yang, ZZ,Ding, XG,&Jiang, J.(2016).Facile synthesis of magnetic-plasmonic nanocomposites as T (1) MRI contrast enhancing and photothermal therapeutic agents.NANO RESEARCH,9(3). |
| MLA | Yang, ZZ,et al."Facile synthesis of magnetic-plasmonic nanocomposites as T (1) MRI contrast enhancing and photothermal therapeutic agents".NANO RESEARCH 9.3(2016). |
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