A cognitive electrophysiological signature differentiates amnestic mild cognitive impairment from normal aging
文献类型：期刊论文
| 作者 | Li, Juan1,2 ; Broster, Lucas S.2; Jicha, Gregory A.3,4; Munro, Nancy B.5; Schmitt, Frederick A.2,3,4; Abner, Erin3,6; Kryscio, Richard3,7,8; Smith, Charles D.3,4; Jiang, Yang2,3
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| 刊名 | ALZHEIMERS RESEARCH & THERAPY
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| 出版日期 | 2017-01-19 |
| 卷号 | 9期号:0页码:1-10 |
| 通讯作者邮箱 | lijuan@psych.ac.cn ; yjiang@uky.edu |
| ISSN号 | 1758-9193 |
| 关键词 | Amnestic mild cognitive impairment Alzheimer's disease Event-related potentials Working memory Early detection |
| 通讯作者 | Li, Juan ; Jiang, Yang |
| 英文摘要 | Background: Noninvasive and effective biomarkers for early detection of amnestic mild cognitive impairment (aMCI) before measurable changes in behavioral performance remain scarce. Cognitive event-related potentials (ERPs) measure synchronized synaptic neural activity associated with a cognitive event. Loss of synapses is a hallmark of the neuropathology of early Alzheimer's disease (AD). In the present study, we tested the hypothesis that ERP responses during working memory retrieval discriminate aMCI from cognitively normal controls (NC) matched in age and education. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Clinical Neurology ; Neurosciences |
| 研究领域[WOS] | Neurosciences & Neurology |
| 关键词[WOS] | EVENT-RELATED POTENTIALS ; ALZHEIMERS ASSOCIATION WORKGROUPS ; WORKING-MEMORY ; DIAGNOSTIC GUIDELINES ; NATIONAL INSTITUTE ; NEURAL MECHANISMS ; DISEASE ; RECOMMENDATIONS ; NEUROPATHOLOGY ; PROGRESSION |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000392149100001 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/21145]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Univ Kentucky, Coll Med, Dept Behav Sci, Lexington, KY 40536 USA 3.Univ Kentucky, Sanders Brown Ctr Aging, Lexington, KY 40536 USA 4.Univ Kentucky, Dept Neurol, Coll Med, Lexington, KY 40536 USA 5.Oak Ridge Natl Lab, Oak Ridge, TN USA 6.Univ Kentucky, Coll Publ Hlth, Dept Epidemiol, Lexington, KY 40536 USA 7.Univ Kentucky, Dept Stat, Lexington, KY 40536 USA 8.Univ Kentucky, Dept Biostat, Coll Publ Hlth, Lexington, KY 40536 USA |
| 推荐引用方式 GB/T 7714 | Li, Juan,Broster, Lucas S.,Jicha, Gregory A.,et al. A cognitive electrophysiological signature differentiates amnestic mild cognitive impairment from normal aging[J]. ALZHEIMERS RESEARCH & THERAPY,2017,9(0):1-10. |
| APA | Li, Juan.,Broster, Lucas S..,Jicha, Gregory A..,Munro, Nancy B..,Schmitt, Frederick A..,...&Jiang, Yang.(2017).A cognitive electrophysiological signature differentiates amnestic mild cognitive impairment from normal aging.ALZHEIMERS RESEARCH & THERAPY,9(0),1-10. |
| MLA | Li, Juan,et al."A cognitive electrophysiological signature differentiates amnestic mild cognitive impairment from normal aging".ALZHEIMERS RESEARCH & THERAPY 9.0(2017):1-10. |
入库方式： OAI收割
来源：心理研究所
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