Cytotoxicity of Triterpenoid Alkaloids from Buxus microphylla against Human Tumor Cell Lines
文献类型：期刊论文
| 作者 | Bai, Shi-Tou1,2; Zhu, Guo-Lei1; Peng, Xing-Rong1,3; Dong, Jin-Run1,3; Yu, Mu-Yuan1 ; Chen, Jian-Chao1,2,3; Wan, Luo-Sheng1,3; Qiu, Ming-Hua1,2,3
|
| 刊名 | MOLECULES
 |
| 出版日期 | 2016-09-01 |
| 卷号 | 21期号:9页码:1 |
| 关键词 | Buxus microphylla triterpenoid alkaloid cytotoxicity |
| 英文摘要 | Three new triterpenoid alkaloids, namely buxmicrophyllines P-R (1-3), were isolated from the twigs and leaves of Buxusmicrophylla. Their structures were elucidated on the basis of NMR and MS spectroscopic analyses. Structurally, compounds 1-3 belong to the 9,10-cycloartane type alkaloids. In addition, compound 3 exhibited moderate cytotoxic activities in vitro against HL-60, SMMC-7221, A-549, MCF-7, and SW480 cell lines (with IC50 values ranging from 4.51 to 15.58 M). |
| 类目[WOS] | Chemistry, Organic |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | STEROIDAL ALKALOIDS ; SEMPERVIRENS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000385479800022 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/33623]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Yunnan Univ Tradit Chinese Med, Sch Tradit Chinese Med, Kunming 650500, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Nat Med Chem, Kunming 650201, Peoples R China |
| 推荐引用方式 GB/T 7714 | Bai, Shi-Tou,Zhu, Guo-Lei,Peng, Xing-Rong,et al. Cytotoxicity of Triterpenoid Alkaloids from Buxus microphylla against Human Tumor Cell Lines[J]. MOLECULES,2016,21(9):1. |
| APA | Bai, Shi-Tou.,Zhu, Guo-Lei.,Peng, Xing-Rong.,Dong, Jin-Run.,Yu, Mu-Yuan.,...&Qiu, Ming-Hua.(2016).Cytotoxicity of Triterpenoid Alkaloids from Buxus microphylla against Human Tumor Cell Lines.MOLECULES,21(9),1. |
| MLA | Bai, Shi-Tou,et al."Cytotoxicity of Triterpenoid Alkaloids from Buxus microphylla against Human Tumor Cell Lines".MOLECULES 21.9(2016):1. |
入库方式： OAI收割
来源：昆明植物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。