Ptotective effects of cycloartane triterpenoides from Passiflora edulis Sims against glutamate-induced neurotoxicity in PC12 cell
文献类型：期刊论文
| 作者 | Xu, Feng-Qing1,2,3; Wang, Ning1 ; Fan, Wei-Wei2,3; Zi, Cheng-Ting2,3; Zhao, Hong-Su1; Hu, Jiang-Miao2,3; Zhou, Jun2,3
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| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2016-12-01 |
| 卷号 | 115期号:1页码:122-127 |
| 关键词 | Passiflora edulis Sims Cycloartane triterpenoid PC12 Glutamate-induced neurotoxicity |
| 英文摘要 | Four new cycloartane triterpenoids, 1 alpha,3 beta-dihydroxy-16-keto-24(31)-en-cycloartane (1), 31-methoxyl-passifloic acid (2), cyclopassifloside XIV (3), and cyclopassifloside XV (4), together with six known compounds (5-10) were isolated from Passiflora edulis Sims. Their structures were elucidated on the basis of extensive spectroscopic analysis. All the compounds were evaluated for protective effects against damage of PC12 cell induced by glutamate according to traditional usage of the herbal medicine, and the results indicated that cycloartane triterpenoids maybe one of the active compositions of P. edulis Sims for the treatment of neurodegenerative disease. (C) 2016 Published by Elsevier B.V. |
| 类目[WOS] | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| 关键词[WOS] | AQUEOUS EXTRACTS ; ALATA ; SAPONINS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000389113300020 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/33755]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Anhui Univ Chinese Med, Hefei 230012, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Nat Med Chem, Kunming 650201, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Feng-Qing,Wang, Ning,Fan, Wei-Wei,et al. Ptotective effects of cycloartane triterpenoides from Passiflora edulis Sims against glutamate-induced neurotoxicity in PC12 cell[J]. FITOTERAPIA,2016,115(1):122-127. |
| APA | Xu, Feng-Qing.,Wang, Ning.,Fan, Wei-Wei.,Zi, Cheng-Ting.,Zhao, Hong-Su.,...&Zhou, Jun.(2016).Ptotective effects of cycloartane triterpenoides from Passiflora edulis Sims against glutamate-induced neurotoxicity in PC12 cell.FITOTERAPIA,115(1),122-127. |
| MLA | Xu, Feng-Qing,et al."Ptotective effects of cycloartane triterpenoides from Passiflora edulis Sims against glutamate-induced neurotoxicity in PC12 cell".FITOTERAPIA 115.1(2016):122-127. |
入库方式： OAI收割
来源：昆明植物研究所
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