The pyrrolidinoindoline alkaloid Psm2 inhibits platelet aggregation and thrombus formation by affecting PI3K/Akt signaling
文献类型：期刊论文
| 作者 | Su, Xing-li1; Su, Wen1; Wang, Ying1; Wang, Yue-hu3,4 ; Ming, Xin5; Kong, Yi1,2
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| 刊名 | ACTA PHARMACOLOGICA SINICA
 |
| 出版日期 | 2016-09-01 |
| 卷号 | 37期号:9页码:1208-1217 |
| 关键词 | Psm2 Selaginellaceae pyrrolidinoindoline alkaloid antiplatelet antithrombosis PI3K/Akt signaling |
| 英文摘要 | Aim: Psm2, one of the pyrrolidinoindoline alkaloids isolated from whole Selaginella moellendorffii plants, has shown a potent antiplatelet activity. In this study, we further evaluated the antiplatelet effects of Psm2, and elucidated the underlying mechanisms. |
| 类目[WOS] | Chemistry, Multidisciplinary ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Chemistry ; Pharmacology & Pharmacy |
| 关键词[WOS] | AGKISTRODON-ACUTUS VENOM ; IN-VITRO ; ANTITHROMBOTIC THERAPY ; SALVIANOLIC ACID ; ANTIPLATELET ; PEPTIDE ; FIBRINOGEN ; ADHESION ; VIVO ; ALPHA(IIB)BETA(3) |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000383046000007 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/33589]  |
| 专题 | 昆明植物研究所_资源植物与生物技术所级重点实验室 |
| 作者单位 | 1.China Pharmaceut Univ, Sch Life Sci & Technol, Nanjing 210009, Peoples R China 2.China Pharmaceut Univ, State Key Lab Nat Med, Nanjing 210009, Peoples R China 3.Chinese Acad Sci, Key Lab Econ Plants & Biotechnol, Kunming Inst Bot, Kunming 650201, Peoples R China 4.Chinese Acad Sci, Yunnan Key Lab Wild Plant Resources, Kunming Inst Bot, Kunming 650201, Peoples R China 5.Univ North Carolina Chapel Hill, UNC Eshelman Sch Pharm, Div Mol Pharmaceut, Chapel Hill, NC 27599 USA |
| 推荐引用方式 GB/T 7714 | Su, Xing-li,Su, Wen,Wang, Ying,et al. The pyrrolidinoindoline alkaloid Psm2 inhibits platelet aggregation and thrombus formation by affecting PI3K/Akt signaling[J]. ACTA PHARMACOLOGICA SINICA,2016,37(9):1208-1217. |
| APA | Su, Xing-li,Su, Wen,Wang, Ying,Wang, Yue-hu,Ming, Xin,&Kong, Yi.(2016).The pyrrolidinoindoline alkaloid Psm2 inhibits platelet aggregation and thrombus formation by affecting PI3K/Akt signaling.ACTA PHARMACOLOGICA SINICA,37(9),1208-1217. |
| MLA | Su, Xing-li,et al."The pyrrolidinoindoline alkaloid Psm2 inhibits platelet aggregation and thrombus formation by affecting PI3K/Akt signaling".ACTA PHARMACOLOGICA SINICA 37.9(2016):1208-1217. |
入库方式： OAI收割
来源：昆明植物研究所
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