Eluent Tolerance and Enantioseparation Recovery of Chiral Packing Materials Based on Chitosan Bis(Phenylcarbamate)-(n-Octyl Urea)s for High Performance Liquid Chromatography
文献类型：期刊论文
| 作者 | Wang, Jing1; Huang, Shao-Hua2 ; Chen, Wei1; Bai, Zheng-Wu1
|
| 刊名 | MOLECULES
 |
| 出版日期 | 2016-11-01 |
| 卷号 | 21期号:11 |
| 关键词 | chitosan chiral packing material durability chiral recognition high performance liquid chromatography |
| 英文摘要 | The goal of the present work was to study the influence of the swelling of chitosan derivatives on the enantioseparation and the separation performance recovery of chiral stationary phases (CSPs) based on these derivatives. Therefore, six chitosan bis(phenylcarbamate)-(n-octyl urea)s were synthesized, which were coated on macroporous 3-aminopropyl silica gel affording new CSPs. Most of the CSPs demonstrated strong enantioseparation capability for the tested chiral compounds. The swelling capacity of the chitosan bis(phenylcarbamate)-(n-octyl urea) s in ethyl acetate, acetone and tetrahydrofuran (THF) was evaluated. Among the chitosan derivatives, the chitosan bis(3,5-dichlorophenylcarbamate)-(n-octyl urea) polymer showed the highest swelling capacity in ethyl acetate and THF. The polymer-based CSPs could be utilized with pure ethyl acetate and a normal phase containing 70% THF, but was damaged by pure THF. On the other hand, the separation performance of the damaged CSP could be recovered after it was allowed to stand for a period of time. The observations are important for the development and application of polysaccharide derivative-based CSPs. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Chemistry, Organic |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | SUPERCRITICAL-FLUID CHROMATOGRAPHY ; STATIONARY PHASES ; POLYSACCHARIDE DERIVATIVES ; SEPARATION ; ENANTIOMERS ; AMYLOSE ; RECOGNITION ; CELLULOSE ; RESOLUTION ; SELECTORS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000389918200110 |
| 源URL | [http://ir.qibebt.ac.cn/handle/337004/9208]  |
| 专题 | 青岛生物能源与过程研究所_条件保障部公共实验室 |
| 作者单位 | 1.Wuhan Inst Technol, Sch Chem & Environm Engn, Wuhan 430073, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biobased Mat, Qingdao 266101, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Jing,Huang, Shao-Hua,Chen, Wei,et al. Eluent Tolerance and Enantioseparation Recovery of Chiral Packing Materials Based on Chitosan Bis(Phenylcarbamate)-(n-Octyl Urea)s for High Performance Liquid Chromatography[J]. MOLECULES,2016,21(11). |
| APA | Wang, Jing,Huang, Shao-Hua,Chen, Wei,&Bai, Zheng-Wu.(2016).Eluent Tolerance and Enantioseparation Recovery of Chiral Packing Materials Based on Chitosan Bis(Phenylcarbamate)-(n-Octyl Urea)s for High Performance Liquid Chromatography.MOLECULES,21(11). |
| MLA | Wang, Jing,et al."Eluent Tolerance and Enantioseparation Recovery of Chiral Packing Materials Based on Chitosan Bis(Phenylcarbamate)-(n-Octyl Urea)s for High Performance Liquid Chromatography".MOLECULES 21.11(2016). |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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