Accumulation of polybrominated diphenyl ethers in the brain compared with the levels in other tissues among different vertebrates from an e-waste recycling site
文献类型：期刊论文
| 作者 | Zhao, Yaxian; Li, Yuanyuan; Qin, Xiaofei; Lou, Qinqin; Qin, Zhanfen |
| 刊名 | ENVIRONMENTAL POLLUTION
 |
| 出版日期 | 2016-11 |
| 卷号 | 218期号:0页码:1334-1341 |
| 关键词 | Polybrominated diphenyl ethers Accumulation Brain Blood-brain barrier Evolution |
| 英文摘要 | This study aimed to investigate the accumulation of polybrominated diphenyl ethers (PBDEs) in the brain compared with that in other tissues among different vertebrates. We collected mice, chickens, ducks, frogs, and fish from an e-waste recycling region in Taizhou, China, and measured PBDE concentrations in brain, liver and muscle tissues. The levels of PBDE in the tissues of mice, chickens, ducks, frogs and fish ranged 0.45-206, 0.06-18.8, 1.83-112, 2.75-108, and 0.02-32.0 ng/g wet weight, respectively. Preferential distribution in the liver and muscle relative to the brain was observed for PBDEs in mice, chickens, ducks and frogs. However, a high retention in the brain compared to the liver and muscle was observed in fish. Comparison of the brain/liver concentration (B/L) ratios revealed differences in PBDEs accumulation in the brain among these vertebrates. PBDEs accumulation in the brain was greatest in fish, followed by frogs, while the lowest accumulation occurred in the brains of mammals and birds. The findings apparently coincided with the evolution of the blood-brain barrier (BBB) across vertebrates, i.e. the BBB of fish might be less efficient than those of mammals, birds and amphibian. Low brominated congeners (such as BDE-28, BDE-47 and BDE-99) were predominant in the brains of investigated vertebrates, whereas BDE-209 was most abundant in liver and muscle tissues of mice, chickens and ducks. Significant differences in B/L ratios among PBDE congeners were found in both mice and chickens (p < 0.05). Particularly in mice, the B/L ratios of PBDE congeners presented a declining trend with increased bromine number. Our findings suggested that low brominated congeners might have a higher capacity to penetrate the BBB and accumulate in the brain, whereas high brominated congeners such as BDE-209 might have less potency to pass through the barrier. Further experimental studies are needed to confirm our findings. (C) 2016 Elsevier Ltd. All rights reserved. |
| 收录类别 | SCI |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/35796]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhao, Yaxian,Li, Yuanyuan,Qin, Xiaofei,et al. Accumulation of polybrominated diphenyl ethers in the brain compared with the levels in other tissues among different vertebrates from an e-waste recycling site[J]. ENVIRONMENTAL POLLUTION,2016,218(0):1334-1341. |
| APA | Zhao, Yaxian,Li, Yuanyuan,Qin, Xiaofei,Lou, Qinqin,&Qin, Zhanfen.(2016).Accumulation of polybrominated diphenyl ethers in the brain compared with the levels in other tissues among different vertebrates from an e-waste recycling site.ENVIRONMENTAL POLLUTION,218(0),1334-1341. |
| MLA | Zhao, Yaxian,et al."Accumulation of polybrominated diphenyl ethers in the brain compared with the levels in other tissues among different vertebrates from an e-waste recycling site".ENVIRONMENTAL POLLUTION 218.0(2016):1334-1341. |
入库方式： OAI收割
来源：生态环境研究中心
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