Antioxidant, cholinesterase inhibition activities and essential oil analysis of Nelumbo nucifera seeds
文献类型：期刊论文
| 作者 | Khan, Shahnaz; Khan, Hidayatullah; Ali, Farman; Ali, Nayab; Khan, Fahim Ullah; Khan, Sami Ullah |
| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 出版日期 | 2016-01 |
| 卷号 | 30期号:11页码:1335-1338 |
| 关键词 | Nelumbo nucifera antioxidant cholinesterase inhibition essential oil GC-MS analysis |
| 英文摘要 | Nelumbo nucifera seeds' essential oil (EO), crude extract and subsequent fractions were evaluated for their DPPH, ABTS and superoxide anion-free radical scavenging and cholinesterase inhibitory activities. The ethyl acetate fraction and EO showed outstanding antioxidant activities with IC50 values of 191, 450g/mL (DPPH), 123, 221g/mL (ABTS) and 69, 370g/mL (superoxide anion). The ethyl acetate fraction and EO also caused significant inhibition of acetylcholinesterase and butyrylcholinesterase with IC50 values of 70 +/- 0.6, 64 +/- 0.8 and 75 +/- 0.3, 58 +/- 0.2, in dose-dependent manner. The first ever gas chromatography-mass spectrometry analysis of the EO obtained from N. nucifera seeds resulted in identification of 19 constituents, mainly comprised of oxygenated sesquiterpenes responsible for their promising bioactivity. The crude and fractions revealed the presence of saponins, flavonoids, steroids, alkaloids, terpenoids and cardiac glycosides in phytochemical investigation. |
| 收录类别 | SCI |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/35802]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Khan, Shahnaz,Khan, Hidayatullah,Ali, Farman,et al. Antioxidant, cholinesterase inhibition activities and essential oil analysis of Nelumbo nucifera seeds[J]. NATURAL PRODUCT RESEARCH,2016,30(11):1335-1338. |
| APA | Khan, Shahnaz,Khan, Hidayatullah,Ali, Farman,Ali, Nayab,Khan, Fahim Ullah,&Khan, Sami Ullah.(2016).Antioxidant, cholinesterase inhibition activities and essential oil analysis of Nelumbo nucifera seeds.NATURAL PRODUCT RESEARCH,30(11),1335-1338. |
| MLA | Khan, Shahnaz,et al."Antioxidant, cholinesterase inhibition activities and essential oil analysis of Nelumbo nucifera seeds".NATURAL PRODUCT RESEARCH 30.11(2016):1335-1338. |
入库方式： OAI收割
来源：生态环境研究中心
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