Environmental Occurrence and Toxicology of Fluorotelomer Alcohols
文献类型：期刊论文
| 作者 | Li Zhongmin; Guo Lianghong |
| 刊名 | PROGRESS IN CHEMISTRY
 |
| 出版日期 | 2016-07 |
| 卷号 | 28期号:7页码:993-1005 |
| 关键词 | fluorotelomer alcohol poly- and perfluoroalkyl substances environmental pollution biotransformation toxicological effects |
| 英文摘要 | Poly- and perfluoroalkyl substances (PFASs) are a family of anthropogenic chemicals widely used in the commercial and industrial applications due to their unique properties of stability, hydrophobicity and lipophobicity. Traditionally, PFASs are produced via two major manufacturing processes; electrochemical fluorination (ECF) and telomerization. Due to their persistence, toxicity and bioaccumulation, ECF-associated chemicals perfluorooctane sulfonic acid (PFOS), its salts and perfluorooctane sulfonyl fluoride (POSF) are placed into the Annex B of the Stockholm Convention (SC) on Persistent Organic Pollutants (POPs) in 2009. The ECF production has also been phased out gradually in the developed countries. However, the production of fluorotelomer alcohols (FTOHs) by telomerization has increased significantly. Recent studies have demonstrated that the biotransformation and abiotic transformation of FTOHs yielded perfluocarboxylic acids (PFCAs), which may be router for the ubiquitous distribution of PFCAs. Besides, some of the FTOHs intermediate metabolites have been demonstrated to be able to covalently bind with various biomolecules and thereby cause serious toxicity, while the final metabolites are showed to cause hepatotoxicity and renal toxicity. Recently, the environmental problems related to FTOHs have become the hotspots in environmental science, toxicology and epidemiology. This paper reviews the research progress on the production status, environmental occurrence, and the toxicities of FTOHs and the related metabolites. Finally, the currently existing problems and trends are discussed. |
| 收录类别 | SCI |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/35849]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Li Zhongmin,Guo Lianghong. Environmental Occurrence and Toxicology of Fluorotelomer Alcohols[J]. PROGRESS IN CHEMISTRY,2016,28(7):993-1005. |
| APA | Li Zhongmin,&Guo Lianghong.(2016).Environmental Occurrence and Toxicology of Fluorotelomer Alcohols.PROGRESS IN CHEMISTRY,28(7),993-1005. |
| MLA | Li Zhongmin,et al."Environmental Occurrence and Toxicology of Fluorotelomer Alcohols".PROGRESS IN CHEMISTRY 28.7(2016):993-1005. |
入库方式： OAI收割
来源：生态环境研究中心
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