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Two-Dimensional Ultrathin MXene Ceramic Nanosheets for Photothermal Conversion
文献类型：期刊论文
| 作者 | Lin, Han1,2; Wang, Xingang1; Yu, Luodan1,2; Chen, Yu1; Shi, Jianlin1 |
| 刊名 | NANO LETTERS
 |
| 出版日期 | 2017 |
| 卷号 | 17期号:1页码:384-391 |
| 关键词 | Ultrathin MXene Ti3C2 nanosheets nanomedicine photothermal conversion tumor therapy |
| 英文摘要 | Ceramic biomaterials have been investigated for several decades, but their potential biomedical applications in cancer therapy have been paid much less attentions, mainly due to their lack of related material functionality for combating the cancer. In this work, we report, for the first time, that MAX ceramic biomaterials exhibit the unique functionality for the photothermal ablation of cancer upon being exfoliated into ultrathin nanosheets within atomic thickness (MXene). As a paradigm, biocompatible Ti3C2 nanosheets (MXenes) were successfully synthesized based on a two-step exfoliation strategy of MAX phase Ti3AlC2 by the combined HF etching and TPAOH intercalation. Especially, the high photothermal-conversion efficiency and in vitro/in vivo photothermal ablation of tumor of Ti3C2 nanosheets (MXenes) were revealed and demonstrated, not only in the intravenous administration of soybean phospholipid modified Ti3C2 nanosheets but also in the localized intratumoral implantation of a phase-changeable PLGA/Ti3C2 organic-inorganic hybrid. This work promises the great potential of Ti3C2 nanosheets (MXenes) as a novel ceramic photothermal agent used for cancer therapy and may arouse much interest in exploring MXene-based ceramic biomaterials to benefit the biomedical applications. |
| WOS标题词 | Science & Technology ; Physical Sciences ; Technology |
| 类目[WOS] | Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter |
| 研究领域[WOS] | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 关键词[WOS] | HIGH VOLUMETRIC CAPACITANCE ; IN-VIVO ; TITANIUM CARBIDE ; DRUG-DELIVERY ; CANCER-CELLS ; THERAPY ; GRAPHENE ; NANOPARTICLES ; NANOCRYSTALS ; MOS2 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000392036600055 |
| 源URL | [http://ir.sic.ac.cn/handle/331005/23375]  |
| 专题 | 上海硅酸盐研究所_高性能陶瓷和超微结构国家重点实验室_期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lin, Han,Wang, Xingang,Yu, Luodan,et al. Two-Dimensional Ultrathin MXene Ceramic Nanosheets for Photothermal Conversion[J]. NANO LETTERS,2017,17(1):384-391. |
| APA | Lin, Han,Wang, Xingang,Yu, Luodan,Chen, Yu,&Shi, Jianlin.(2017).Two-Dimensional Ultrathin MXene Ceramic Nanosheets for Photothermal Conversion.NANO LETTERS,17(1),384-391. |
| MLA | Lin, Han,et al."Two-Dimensional Ultrathin MXene Ceramic Nanosheets for Photothermal Conversion".NANO LETTERS 17.1(2017):384-391. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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