Alkaline biodegradable implants for osteoporotic bone defects-importance of microenvironment pH
文献类型：期刊论文
| 作者 | Liu, W.1,2; Wang, T.2; Yang, C.3; Darvell, B. W.4; Wu, J.1; Lin, K.5; Chang, J.5; Pan, H.2; Lu, W. W.1 |
| 刊名 | OSTEOPOROSIS INTERNATIONAL
 |
| 出版日期 | 2016 |
| 卷号 | 27期号:1页码:93-104 |
| 关键词 | Bone remodeling In vivo microenvironment pH Orthopaedic biomaterials Osteoporotic bone defect |
| 英文摘要 | A Summary Change of microenvironment pH by biodegradable implants may ameliorate unbalanced osteoporotic bone remodeling. The present work demonstrated that a weak alkaline condition stimulated osteoblasts differentiation while suppressed osteoclast generation. In vivo, implants with an alkaline microenvironment pH (monitored by a pH microelectrode) exhibited a promising healing effect for the repair of osteoporotic bone defects. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Endocrinology & Metabolism |
| 研究领域[WOS] | Endocrinology & Metabolism |
| 关键词[WOS] | IN-VIVO ; BIOMATERIALS ; OSTEOBLASTS ; OSTEOCLAST ; CELLS ; MICROELECTRODES ; MINERALIZATION ; FRACTURES ; VITRO ; RAT |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000369525500012 |
| 源URL | [http://ir.sic.ac.cn/handle/331005/23260]  |
| 专题 | 上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文 |
| 作者单位 | 1.Univ Hong Kong, Fac Med, Dept Orthopaed & Traumatol, Pokfulam, Hong Kong, Peoples R China 2.Chinese Acad Sci, Shenzhen Inst Adv Technol, Shenzhen Key Lab Marine Biomed Mat, Shenzhen, Peoples R China 3.Shenzhen Univ, Sch Med, Shenzhen 518052, Peoples R China 4.Kuwait Univ, Fac Dent, Dept Bioclin Sci, Dent Mat Sci, Kuwait, Kuwait 5.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, W.,Wang, T.,Yang, C.,et al. Alkaline biodegradable implants for osteoporotic bone defects-importance of microenvironment pH[J]. OSTEOPOROSIS INTERNATIONAL,2016,27(1):93-104. |
| APA | Liu, W..,Wang, T..,Yang, C..,Darvell, B. W..,Wu, J..,...&Lu, W. W..(2016).Alkaline biodegradable implants for osteoporotic bone defects-importance of microenvironment pH.OSTEOPOROSIS INTERNATIONAL,27(1),93-104. |
| MLA | Liu, W.,et al."Alkaline biodegradable implants for osteoporotic bone defects-importance of microenvironment pH".OSTEOPOROSIS INTERNATIONAL 27.1(2016):93-104. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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