Amorphous calcium phosphate, hydroxyapatite and poly(D,L-lactic acid) composite nanofibers: Electrospinning preparation, mineralization and in vivo bone defect repair
文献类型：期刊论文
| 作者 | Zhang, Hao1; Fu, Qi-Wei1; Sun, Tuan-Wei2; Chen, Feng2; Qi, Chao2; Wu, Jin2; Cai, Zhu-Yun1; Qian, Qi-Rong1; Zhu, Ying-Jie2 |
| 刊名 | COLLOIDS AND SURFACES B-BIOINTERFACES
 |
| 出版日期 | 2015-12-01 |
| 卷号 | 136页码:27-36 |
| 关键词 | Calcium phosphate Hydroxyapatite Nanofiber Electrospinning Mineralization Bone defect repair |
| 英文摘要 | Due to the outstanding bioactivity and biocompatibility, calcium phosphate (CaP) based materials have been widely investigated for applications in the biomedical fields. In this study, amorphous calcium phosphate (ACP) nanospheres and hydroxyapatite (HA) nanorods have been prepared and hybridized with poly(D,L-lactic acid) (PLA) to fabricate the composite nanofibers through electrospinning. The as-prepared ACP-PLA and HA-PLA composite nanofibers exhibit favorable mineralization behaviors in simulated body fluid (SBF). In the mineralization process, the ACP nanospheres and HA nanorods play an important role in the formation of HA nanosheets on the surface of composite nanofibers. The ACP-PLA and HA-PIA composite nanofibers show a high biocompatibility. The in vivo bone defect repair properties of the ACP-PLA and HA-PEA composite nanofibers are preliminarily investigated. The as-prepared ACP-PLA and HA-PEA composite nanofibers have promising applications in the biomedical fields. (C) 2015 Elsevier B.V. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences ; Technology |
| 类目[WOS] | Biophysics ; Chemistry, Physical ; Materials Science, Biomaterials |
| 研究领域[WOS] | Biophysics ; Chemistry ; Materials Science |
| 关键词[WOS] | DRUG-DELIVERY ; TISSUE ; NANOPARTICLES ; SCAFFOLDS ; BIOMINERALIZATION ; PROLIFERATION ; IMPLANTS ; NANORODS ; BEHAVIOR ; CELLS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000367408100005 |
| 源URL | [http://ir.sic.ac.cn/handle/331005/23296]  |
| 专题 | 上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文 |
| 作者单位 | 1.Second Mil Med Univ, Changzheng Hosp, Dept Orthoped, Shanghai 200003, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Hao,Fu, Qi-Wei,Sun, Tuan-Wei,et al. Amorphous calcium phosphate, hydroxyapatite and poly(D,L-lactic acid) composite nanofibers: Electrospinning preparation, mineralization and in vivo bone defect repair[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2015,136:27-36. |
| APA | Zhang, Hao.,Fu, Qi-Wei.,Sun, Tuan-Wei.,Chen, Feng.,Qi, Chao.,...&Zhu, Ying-Jie.(2015).Amorphous calcium phosphate, hydroxyapatite and poly(D,L-lactic acid) composite nanofibers: Electrospinning preparation, mineralization and in vivo bone defect repair.COLLOIDS AND SURFACES B-BIOINTERFACES,136,27-36. |
| MLA | Zhang, Hao,et al."Amorphous calcium phosphate, hydroxyapatite and poly(D,L-lactic acid) composite nanofibers: Electrospinning preparation, mineralization and in vivo bone defect repair".COLLOIDS AND SURFACES B-BIOINTERFACES 136(2015):27-36. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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