CO₂是目前最大的碳源之一, 将CO₂用于合成有机化合物无疑是清洁能源利用的一种新策略, 作为CO₂参与有机合成反应的主要产物, 羧酸及其衍生物也有着广泛的应用. 在众多CO₂参与的羧化反应方法中, C—H键与CO₂的直接羧化反应是最高效的同时也是目前研究十分热门的一类有机化学反应. 对近年来CO₂与不同杂化态C—H键的直接羧化反应的研究进行总结, 主要讲述过渡金属催化的反应体系.

Carbon dioxide represents the most abundant carbon source in the world. It is obvious that the utilization of CO₂ to generate chemical products will provide a new strategy for clean energy. Meanwhile, as the main product of CO₂ reactions, carboxylic acids and derivatives have wide application. Among various CO₂ involved carboxylation reactions, the direct carboxylation of C-H bond with CO₂ has attracted much attention recently, which lies in its high efficiency for the synthesis of carboxylic acids. This review summarizes the direct carboxylation of different hybrid C-H bonds with CO₂ in recent years, which focus on transition metal catalyzed reactions for the synthesis of carboxylic acids and its derivatives from CO₂.