Lab on smartphone with interfaced electrochemical chips for on-site gender verification
文献类型：期刊论文
| 作者 | Deng, WP; Dou, YZ; Song, P; Xu, H; Aldalbahi, A; Chen, N; El-Sayed, NN; Gao, JM; Lu, JX; Song, SP |
| 刊名 | JOURNAL OF ELECTROANALYTICAL CHEMISTRY
 |
| 出版日期 | 2016 |
| 卷号 | 777页码:117-122 |
| ISSN号 | 1572-6657 |
| 关键词 | On site detection Electrochemical Biosensor Gender verification Forensic |
| 通讯作者 | Zuo, XL (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Div Phys Biol, Shanghai 201800, Peoples R China. ; Zuo, XL (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai Synchrotron Radiat Facil, Bioimaging Ctr, Shanghai 201800, Peoples R China. ; Gao, JM (reprint author), Wenzhou Med Univ, Sch Med Lab Sci & Life Sci, Wenzhou 325035, Peoples R China. |
| 英文摘要 | On-site detection of biomarkers in biofluids found at the crime scene is critically important forensic analysis. However, it remains difficult due to the lack of portable, fast and cheap on-site analytical devices. Traditional methods including polymerase chain reaction (PCR) and electrophoresis requires complicated instrumentation and critical environment. Optical analytical methods can be affected by intrinsic adsorption of complicated sample such as serum. In response, we developed a smartphone-interfaced electrochemical chip device for on-site gender verification. The detection is based on the known difference of biomarkers (creatine kinase (CR) and alanine transaminase (ALT)) between male and female groups. Enzyme cascade reaction converted the enzyme level in biofluids to the consumption of NADH, which can be electrochemically detected by our designed electrochemical chip. Our device retained the capability of gender verification when used in serum and serum stains. The detection can be completed in 20 min. Gender verification of real samples (39 serum samples) demonstrated excellent sensitivity and specificity of this smartphone based device. (C) 2016 Elsevier B.V. All rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000383298100015 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/26556]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Deng, WP,Dou, YZ,Song, P,et al. Lab on smartphone with interfaced electrochemical chips for on-site gender verification[J]. JOURNAL OF ELECTROANALYTICAL CHEMISTRY,2016,777:117-122. |
| APA | Deng, WP.,Dou, YZ.,Song, P.,Xu, H.,Aldalbahi, A.,...&Zuo, XL.(2016).Lab on smartphone with interfaced electrochemical chips for on-site gender verification.JOURNAL OF ELECTROANALYTICAL CHEMISTRY,777,117-122. |
| MLA | Deng, WP,et al."Lab on smartphone with interfaced electrochemical chips for on-site gender verification".JOURNAL OF ELECTROANALYTICAL CHEMISTRY 777(2016):117-122. |
入库方式： OAI收割
来源：上海应用物理研究所
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