Familial risk for lung cancer (Review)
文献类型：期刊论文
| 作者 | Kanwal M[*]1,2; Ding XJ1; Cao Y1 |
| 刊名 | ONCOLOGY LETTERS
 |
| 出版日期 | 2017 |
| 卷号 | 13期号:X页码:535-542, |
| 关键词 | familial cancer lung cancer genetic factor environmen |
| 通讯作者 | madiha_k14@hotmail.com |
| 英文摘要 | Lung cancer, which has a low survival rate, is a leading cause of cancer-associated mortality worldwide. Smoking and air pollution are the major causes of lung cancer; however, numerous studies have demonstrated that genetic factors also contribute to the development of lung cancer. A family history of lung cancer increases the risk for the disease in both smokers and never-smokers. This review focuses on familial lung cancer, in particular on the familial aggregation of lung cancer. The development of familial lung cancer involves shared environmental and genetic factors among family members. Familial lung cancer represents a good model for investigating the association between environmental and genetic factors, as well as for identifying susceptibility genes for lung cancer. In addition, studies on familial lung cancer may help to elucidate the etiology and mechanism of lung cancer, and may identify novel biomarkers for early detection and diagnosis, targeted therapy and improved prevention strategies. This review presents the aetiology and molecular biology of lung cancer and then systematically introduces and discusses several aspects of familial lung cancer, including the characteristics of familial lung cancer, population-based studies on familial lung cancer and the genetics of familial lung cancer. |
| 收录类别 | SCI |
| 资助信息 | This study was supported by the 973 Program (grant no. 2011CB510104) and the Natural Science Foundation of China (grant no. 81272617). Furthermore, the study was sponsored by the CAS-TWAS President's Fellowship for Inter- national PhD Students (MK). |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/11008]  |
| 专题 | 昆明动物研究所_分子病理学 |
| 作者单位 | 1.Laboratory of Molecular and Experimental Pathology, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223 2.Kunming College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, P.R. China |
| 推荐引用方式 GB/T 7714 | Kanwal M[*],Ding XJ,Cao Y. Familial risk for lung cancer (Review)[J]. ONCOLOGY LETTERS,2017,13(X):535-542,. |
| APA | Kanwal M[*],Ding XJ,&Cao Y.(2017).Familial risk for lung cancer (Review).ONCOLOGY LETTERS,13(X),535-542,. |
| MLA | Kanwal M[*],et al."Familial risk for lung cancer (Review)".ONCOLOGY LETTERS 13.X(2017):535-542,. |
入库方式： OAI收割
来源：昆明动物研究所
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