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Identification of MHC class I sequences in four species of Macaca of China

文献类型：期刊论文

作者Yan X1,2; Li AX1; Zeng L1; Cao YH1,3; He JB2; Lv LB4; Sui LH1; Ye HH1; Fan JW1; Cui XX1
刊名IMMUNOGENETICS
出版日期2013
卷号65期号:12页码:851-859
关键词Identification MHC class I Four species Macaca
通讯作者laxszz@aliyun.com
合作状况其它
英文摘要Tibetan macaques (Macaca thibetana), stump-tailed macaques (M. arctoides), Assamese macaques (M. assamensis), and northern pig-tailed macaques (M. leonina) are four major species of Macaca in China. In order to effectively use these species in biomedical research, thorough investigations of their MHC immunogenetics are required. In this study, we identified MHC class I sequences using cDNA cloning and sequencing on a cohort of six M. thibetana, three M. arctoides, three M. assamensis, and three M. leonina derived from Sichuan and Yunnan provinces of China. Eighty new alleles were identified, including 26 MHC-A alleles, 46 MHC-B alleles, and 8 MHC-I alleles. Among them, Math-A1*126:01, Math-B*190:01, Math-B*191:01, Math-B*192:01, Maar-A1*127:01, Maar-A1*129:01, and Maas-A1*128:01 represent lineages that had not been reported earlier in Macaca. Phylogenetic analyses show that no obvious separation of lineages among these species of Macaca. This study provides important information about the MHC immunogenetics for the four major species of Chinese macaques and adds value to these species as model organisms in biomedical research.
收录类别SCI
资助信息This work was supported by the National Natural Science Foundation of China (Grant No. 31071987 and No. 31272387).
语种英语
WOS记录号WOS:000326923600003
公开日期2013-12-09
源URL[http://159.226.149.42:8088/handle/152453/7719]  
专题昆明动物研究所_中国科学院昆明灵长类研究中心
作者单位1.Laboratory Animal Center, Academy of Military Medical Science, Beijing 100071, China
2.College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang 110161, China
3.Collge of Life Sciences, Tarim University, Alaer 84330, China
4.Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
推荐引用方式
GB/T 7714		 Yan X,Li AX,Zeng L,et al. Identification of MHC class I sequences in four species of Macaca of China[J]. IMMUNOGENETICS,2013,65(12):851-859.
APA Yan X.,Li AX.,Zeng L.,Cao YH.,He JB.,...&Sun ZZ[*].(2013).Identification of MHC class I sequences in four species of Macaca of China.IMMUNOGENETICS,65(12),851-859.
MLA Yan X,et al."Identification of MHC class I sequences in four species of Macaca of China".IMMUNOGENETICS 65.12(2013):851-859.

入库方式： OAI收割

来源：昆明动物研究所

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