Determination of parabens in domestic sewage by isotope-coded derivatization coupled with high performance liquid chromatography-tandem mass spectrometry
文献类型：期刊论文
| 作者 | Che, Dandan1; Sun, Zhiwei1; Cheng, Jie1; Dou, Kun1; Ji, Zhongyin2,3; Chen, Guang3; Li, Guoliang3; You, Jinmao2,3 |
| 刊名 | microchemical journal
 |
| 出版日期 | 2017 |
| 卷号 | 130页码:420-427 |
| 关键词 | Isotope-coded derivatization reagent Parabens High performance liquid chromatography Mass spectrometry |
| 英文摘要 | we have established an isotope labeling protocol for determining parabens in wastewater, based on a pair of isotope-coded derivatization reagents, by high performance liquid chromatography (lc) and electrospray mass spectrometry (esi-ms). the pair of reagents used in our work were d(0)-10-methylacridone-2-sulfonyl chloride (d(0)-masc, light form) and d(3)-10-methylacridone-2-sulfonyl chloride (d(3)-masc, heavy form). d(0)-masc and d(3)-masc could easily derivatize parabens at 55 degrees c for 7.5 min in the mixture of bicarbonate and acetonitrile (1:1 v/v). it is shown that the derivatization offers 1-2 orders of magnitude signal enhancement over underivatized counterparts. the global isotope internal standard technology was employed for quantification analysis with d(3)-masc-paraben as internal standard for corresponding d(0)-masc-paraben. in addition, homologous internal standard was simultaneously used to correct derivatization processes. the obtained double internal standard calibration curves for parabens were linear over the range of 1-500 nmol l-1 (r > 0.997). the isotope coded derivatization based quantification method was precise and practical with rsd <= 3.6% and accuracy ranged 96.5 to 104.7%. the proposed method has also been successfully applied to the quantification of parabens in domestic sewage samples with precisions <= 5.2% and recoveries >= 87.9%. five kinds of paraben including methylparaben, ethylparaben, propylparaben, butylparaben, and benzylparaben were detected in the tested samples. the quantitative results indicated that parabens were at nmol l-1 level or lower, and ethylparaben were the most abundant, followed by methylparaben, propylparaben and butylparaben. it has been demonstrated that the isotope-coded derivatization reagents are useful for accurate quantification of analytes having target functional groups in real samples. (c) 2016 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | bar sorptive extraction ; solid-phase dispersion ; relative quantification ; methyl triclosan ; fatty-acids ; metabolites ; water ; reagents ; samples ; ms |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000390072400058 |
| 源URL | [http://ir.nwipb.ac.cn/handle/363003/6645]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 作者单位 | 1.Qufu Normal Univ, Key Lab Life Organ Anal Shandong Prov, Qufu 273165, Peoples R China 2.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining, Peoples R China 3.Key Lab Pharmaceut Intermediates & Nat Prod, Qufu 273165, Peoples R China |
| 推荐引用方式 GB/T 7714 | Che, Dandan,Sun, Zhiwei,Cheng, Jie,et al. Determination of parabens in domestic sewage by isotope-coded derivatization coupled with high performance liquid chromatography-tandem mass spectrometry[J]. microchemical journal,2017,130:420-427. |
| APA | Che, Dandan.,Sun, Zhiwei.,Cheng, Jie.,Dou, Kun.,Ji, Zhongyin.,...&You, Jinmao.(2017).Determination of parabens in domestic sewage by isotope-coded derivatization coupled with high performance liquid chromatography-tandem mass spectrometry.microchemical journal,130,420-427. |
| MLA | Che, Dandan,et al."Determination of parabens in domestic sewage by isotope-coded derivatization coupled with high performance liquid chromatography-tandem mass spectrometry".microchemical journal 130(2017):420-427. |
入库方式： OAI收割
来源：西北高原生物研究所
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