New monoterpenes from stalks and infructescence of Sibiraea leavigata
文献类型：期刊论文
| 作者 | Zhao, Jian-Qiang1,5; Wang, Yan-Ming2,3,5; Lv, Jun-Jiang4; Wang, Shuo1; Mei, Li-Juan1; Tao, Yan-Duo1 |
| 刊名 | phytochemistry letters
 |
| 出版日期 | 2016-12-01 |
| 卷号 | 18页码:1-4 |
| 关键词 | Monoterpenes Sibiraea leavigata Cytotoxic activity |
| 英文摘要 | chemical investigation of the ethanol extract of the stalks and infructescence of sibiraea leavigata led to the isolation of two new monoterpenes named (4r)-2-(2-hydroxy-4-methyl-3-pentenyl) furan-2(5h)one (1) and (2r, 4r)-2-(2-hydroxyethyl)-4-(2-methyl-1-propenyl) furan-5h-2-one (2) along with eight known phenylpropanoids (3-10). their structures were established on the basis of the interpretation of spectroscopic data and electronic circular dichroism (ecd) calculations. in addition, all of these isolates were evaluated for their cytotoxic activity. the results showed that compound 3 displayed moderate cytotoxicity with ic50 values ranging from 10.8 to 49.2 mu g ml(-1) against five cell lines. while 1 showed selective promotion effects on proliferation of gastric cancer mgc803 and rsc96 cell lines. (c) 2016 phytochemical society of europe. published by elsevier ltd. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine |
| 类目[WOS] | plant sciences ; oncology |
| 研究领域[WOS] | plant sciences ; oncology |
| 关键词[WOS] | constituents ; angustata |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000389521800001 |
| 源URL | [http://ir.nwipb.ac.cn/handle/363003/6648]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 作者单位 | 1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810008, Peoples R China 2.Chinese Acad Sci, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 4.Chongqing Univ, Chem & Chem Engn Coll, Chongqing 400030, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Jian-Qiang,Wang, Yan-Ming,Lv, Jun-Jiang,et al. New monoterpenes from stalks and infructescence of Sibiraea leavigata[J]. phytochemistry letters,2016,18:1-4. |
| APA | Zhao, Jian-Qiang,Wang, Yan-Ming,Lv, Jun-Jiang,Wang, Shuo,Mei, Li-Juan,&Tao, Yan-Duo.(2016).New monoterpenes from stalks and infructescence of Sibiraea leavigata.phytochemistry letters,18,1-4. |
| MLA | Zhao, Jian-Qiang,et al."New monoterpenes from stalks and infructescence of Sibiraea leavigata".phytochemistry letters 18(2016):1-4. |
入库方式： OAI收割
来源：西北高原生物研究所
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