中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Triterpenoids of Chrysosplenium carnosum

文献类型:期刊论文

作者Lu, Meng-ya1; Liao, Zhi-xin1; Ji, Lan-ju2; Sun, Hong-fa2
刊名fitoterapia
出版日期2013-03-01
卷号85页码:119-124
关键词Chrysosplenium carnosum Hook. f. et Thoms. Triterpenoid Anti-tumor activity
英文摘要a phytochemical study of the ethanolic extract of chrysosplenium carnosum hook. f. et thoms. led to the isolation of two new oleanane-type triterpenoids, 6 beta-hydroxy-3-oxoolean-12-en-27-oic acid (1) and 3 beta, 21 alpha-dihydroxyolean-12-en-27-oic acid (2), along with fourteen known compounds (3-16), all of which were isolated from this plant for the first time. the structures of these compounds were established on the basis of spectroscopic methods. compounds 1-4 were evaluated for their in vitro anti-tumor activities on b16f10, sp2/0 and hep-g2 cells lines. compounds 1,3 and 4 exhibited strong inhibitory activity against b16f10 and sp2/0 cells' growth, compared with moderate cytotoxic activity against hep-g2 cells. however, compound 2 showed to be inactive against these tumor cells. (c) 2013 elsevier b.v. all rights reserved.
WOS标题词science & technology ; life sciences & biomedicine
类目[WOS]chemistry, medicinal ; pharmacology & pharmacy
研究领域[WOS]pharmacology & pharmacy
关键词[WOS]aceriphyllum-rossii ; astilbe-chinensis ; flavonoids ; cytotoxicity ; grayanum ; cells
收录类别SCI
语种英语
WOS记录号WOS:000317172000018
源URL[http://ir.nwipb.ac.cn/handle/363003/6681]  
专题西北高原生物研究所_中国科学院西北高原生物研究所
作者单位1.Southeast Univ, Sch Chem & Chem Engn, Dept Pharmaceut Engn, Nanjing 211189, Jiangsu, Peoples R China
2.Chinese Acad Sci, Northweast Inst Plateau Biol, Xining 810008, Peoples R China
推荐引用方式
GB/T 7714
Lu, Meng-ya,Liao, Zhi-xin,Ji, Lan-ju,et al. Triterpenoids of Chrysosplenium carnosum[J]. fitoterapia,2013,85:119-124.
APA Lu, Meng-ya,Liao, Zhi-xin,Ji, Lan-ju,&Sun, Hong-fa.(2013).Triterpenoids of Chrysosplenium carnosum.fitoterapia,85,119-124.
MLA Lu, Meng-ya,et al."Triterpenoids of Chrysosplenium carnosum".fitoterapia 85(2013):119-124.

入库方式: OAI收割

来源:西北高原生物研究所

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