中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Racemic alkaloids from the fungus Ganoderma cochlear

文献类型:期刊论文

作者Wang, Xin-Long1,2; Dou, Man2,3; Luo, Qi2; Cheng, Li-Zhi2,4; Yan, Yong-Ming2; Li, Rong-Tao3; Cheng, Yong-Xian1,2
刊名FITOTERAPIA
出版日期2017
卷号116期号:1页码:93-98
关键词Ganoderma cochlear Alkaloids ECD calculations Racemates Biosynthesis
英文摘要Seven pairs of new alkaloid enantiomers, ganocochlearines C-I (1, 3-8), and three pairs of known alkaloids were isolated from the fruiting bodies of Ganoderma cochlear. The chemical structures of new compounds were elucidated on the basis of 1D and 2D NMR data. The absolute configurations of compounds 1,3-10 were assigned by ECD calculations. Biological activities of these isolates against renal fibrosis were accessed in rat normal or diseased renal interstitial fibroblast cells. Importantly, the plausible biosynthetic pathway for this class of alkaloids was originally proposed. (C) 2016 Elsevier B.V. All rights reserved.
类目[WOS]Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]METABOLITES ; LUCIDUM ; MEROTERPENOIDS ; INHIBITORS ; POTENT
收录类别SCI
语种英语
WOS记录号WOS:000392779200014
源URL[http://ir.kib.ac.cn/handle/151853/45766]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Henan Univ Tradit Chinese Med, Zhengzhou 450008, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
3.Kunming Univ Sci & Technol, Fac Life Sci & Engn, Kunming 650500, Peoples R China
4.Guangdong Pharmaceut Univ, Guangzhou 510006, Guangdong, Peoples R China
推荐引用方式
GB/T 7714
Wang, Xin-Long,Dou, Man,Luo, Qi,et al. Racemic alkaloids from the fungus Ganoderma cochlear[J]. FITOTERAPIA,2017,116(1):93-98.
APA Wang, Xin-Long.,Dou, Man.,Luo, Qi.,Cheng, Li-Zhi.,Yan, Yong-Ming.,...&Cheng, Yong-Xian.(2017).Racemic alkaloids from the fungus Ganoderma cochlear.FITOTERAPIA,116(1),93-98.
MLA Wang, Xin-Long,et al."Racemic alkaloids from the fungus Ganoderma cochlear".FITOTERAPIA 116.1(2017):93-98.

入库方式: OAI收割

来源:昆明植物研究所

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