中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Three New Ergot Alkaloids from the Fruiting Bodies of Xylaria nigripes (Kl.) Sacc.

文献类型:期刊论文

作者Hu, Dongbao1,2; Li, Ming1
刊名CHEMISTRY & BIODIVERSITY
出版日期2017
卷号14期号:1
关键词Xylaria nigripes Ergot alkaloids DFT CETP Inhibitory activity
英文摘要Three new ergot alkaloids, xylanigripones A - C (1-3) together with three known compounds, agroclavine (4), 8,9-didehydro-10-hydroxy-6,8-dimethylergolin (5), and (6S)-agroclavine N-oxide (6) were isolated from the fungus Xylaria nigripes (Kl.) Sacc. Their structures were elucidated by comprehensive spectroscopic analyses and high-resolution mass spectrometry as well as by comparison with the literature. The absolute configuration was determined by Density Functional Theory (DFT) calculation methods. In addition, all of the compounds were evaluated for bioactivity via a cytotoxicity assay, an acetylcholinesterase inhibition assay and a cholesterol ester transfer protein inhibition assay.
类目[WOS]Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]ELECTRONIC CIRCULAR-DICHROISM ; ABSOLUTE-CONFIGURATION ; OPTICAL-ROTATION ; CHEMICAL-SHIFTS ; CULTURES ; CLAVICEPS
收录类别SCI
语种英语
WOS记录号WOS:000394421900010
源URL[http://ir.kib.ac.cn/handle/151853/46042]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Yuxi Normal Univ, Coll Resource & Environm, Yuxi 653100, Peoples R China
2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Lanhei Rd 132, Kunming 650201, Peoples R China
推荐引用方式
GB/T 7714
Hu, Dongbao,Li, Ming. Three New Ergot Alkaloids from the Fruiting Bodies of Xylaria nigripes (Kl.) Sacc.[J]. CHEMISTRY & BIODIVERSITY,2017,14(1).
APA Hu, Dongbao,&Li, Ming.(2017).Three New Ergot Alkaloids from the Fruiting Bodies of Xylaria nigripes (Kl.) Sacc..CHEMISTRY & BIODIVERSITY,14(1).
MLA Hu, Dongbao,et al."Three New Ergot Alkaloids from the Fruiting Bodies of Xylaria nigripes (Kl.) Sacc.".CHEMISTRY & BIODIVERSITY 14.1(2017).

入库方式: OAI收割

来源:昆明植物研究所

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