KinetochoreDB: a comprehensive online resource for the kinetochore and its related proteins
文献类型：期刊论文
| 作者 | Li, Chen1,2; Androulakis, Steve3; Buckle, Ashley M.1,2; Song, Jiangning1,2,4,5,6 |
| 刊名 | DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
 |
| 出版日期 | 2016-03-17 |
| 期号 | 2016 |
| 英文摘要 | KinetochoreDB is an online resource for the kinetochore and its related proteins. It provides comprehensive annotations on 1554 related protein entries in terms of their amino acid sequence, protein domain context, protein 3D structure, predicted intrinsically disordered region, protein-protein interaction, post-translational modification site, functional domain and key metabolic/signaling pathways, integrating several public databases, computational annotations and experimental results. KinetochoreDB provides interactive and customizable search and data display functions that allow users to interrogate the database in an efficient and user-friendly manner. It uses PSI-BLAST searches to retrieve the homologs of all entries and generate multiple sequence alignments that contain important evolutionary information. This knowledgebase also provides annotations of single point mutations for entries with respect to their pathogenicity, which may be useful for generation of new hypotheses on their functions, as well as follow-up studies of human diseases. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Mathematical & Computational Biology |
| 研究领域[WOS] | Mathematical & Computational Biology |
| 关键词[WOS] | DATABASE ; MUTATIONS ; GENE ; GENERATION ; SITE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000374090200002 |
| 源URL | [http://124.16.173.210/handle/834782/2252]  |
| 专题 | 天津工业生物技术研究所_结构生物信息学和整合系统生物学实验室 宋江宁_期刊论文 |
| 作者单位 | 1.Monash Univ, Fac Med, Biomed Discovery Inst, Infect & Immun Program, Melbourne, Vic 3800, Australia 2.Monash Univ, Fac Med, Dept Biochem & Mol Biol, Melbourne, Vic 3800, Australia 3.Monash Univ, Monash Bioinformat Platform, Melbourne, Vic 3800, Australia 4.Monash Univ, Monash Ctr Data Sci, Fac Informat Technol, Melbourne, Vic 3800, Australia 5.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Natl Engn Lab Ind Enzymes, Tianjin 300308, Peoples R China 6.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Key Lab Syst Microbial Biotechnol, Tianjin 300308, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Chen,Androulakis, Steve,Buckle, Ashley M.,et al. KinetochoreDB: a comprehensive online resource for the kinetochore and its related proteins[J]. DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION,2016(2016). |
| APA | Li, Chen,Androulakis, Steve,Buckle, Ashley M.,&Song, Jiangning.(2016).KinetochoreDB: a comprehensive online resource for the kinetochore and its related proteins.DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION(2016). |
| MLA | Li, Chen,et al."KinetochoreDB: a comprehensive online resource for the kinetochore and its related proteins".DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION .2016(2016). |
入库方式： OAI收割
来源：天津工业生物技术研究所
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