The role of conformational flexibility in Baeyer-Villiger monooxygenase catalysis and structure
文献类型：期刊论文
| 作者 | Yachnin, Brahm J.1,6; Lau, Peter C. K.3,4,5,7; Berghuis, Albert M.1,2,6 |
| 刊名 | BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
 |
| 出版日期 | 2016-12-01 |
| 卷号 | 1864期号:12页码:1641-1648 |
| 关键词 | Baeyer-Villiger monooxygenase Small-angle X-ray scattering (SAXS) Isothermal titration calorimetry (ITC) Protein flexibility Enzyme mechanism Enzyme catalysis |
| 英文摘要 | Background: The Baeyer-Villiger monooxygenases (BMVOs) are a group of microbial enzymes that have garnered interest as industrial biocatalysts. While great strides have been made in recent years to understand the mechanism of these enzymes from a structural perspective, our understanding remains incomplete. In particular, the role of a twenty residue loop (residues 487-504), which we refer to as the "Control Loop," that is observed in either an ordered or disordered state in various crystal structures remains unclear. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 关键词[WOS] | X-RAY-SCATTERING ; CYCLOHEXANONE MONOOXYGENASE ; ACINETOBACTER NCIB-9871 ; CRYSTAL-STRUCTURE ; OXYGENASE ; PROTEINS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000386861100002 |
| 源URL | [http://124.16.173.210/handle/834782/2297]  |
| 专题 | 天津工业生物技术研究所_酶工程实验室 马延和 _期刊论文 |
| 作者单位 | 1.McGill Univ, Dept Biochem, 3649 Promenade Sir William Oster,Bellini Pavil, Montreal, PQ H3G 0B1, Canada 2.McGill Univ, Dept Microbiol & Immunol, 3649 Promenade Sir William Oster,Bellini Pavil, Montreal, PQ H3G 0B1, Canada 3.McGill Univ, Dept Microbiol & Immunol, 3775 Univ St, Montreal, PQ H3A 2B4, Canada 4.McGill Univ, Dept Chem, 3775 Univ St, Montreal, PQ H3A 2B4, Canada 5.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Natl Engn Lab Ind Enzymes, 32 Xi Qi Dao, Tianjin 300308, Tianjin, Peoples R China 6.PROTEO, Grp Rech GRASP, Montreal, PQ, Canada 7.FQRNT Ctr Green Chem & Catalysis, Montreal, PQ, Canada |
| 推荐引用方式 GB/T 7714 | Yachnin, Brahm J.,Lau, Peter C. K.,Berghuis, Albert M.. The role of conformational flexibility in Baeyer-Villiger monooxygenase catalysis and structure[J]. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS,2016,1864(12):1641-1648. |
| APA | Yachnin, Brahm J.,Lau, Peter C. K.,&Berghuis, Albert M..(2016).The role of conformational flexibility in Baeyer-Villiger monooxygenase catalysis and structure.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS,1864(12),1641-1648. |
| MLA | Yachnin, Brahm J.,et al."The role of conformational flexibility in Baeyer-Villiger monooxygenase catalysis and structure".BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1864.12(2016):1641-1648. |
入库方式： OAI收割
来源：天津工业生物技术研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。