A novel strategy for protein production using non-classical secretion pathway in Bacillus subtilis
文献类型：期刊论文
| 作者 | Chen, Jingqi2; Zhao, Liuqun2; Fu, Gang1,2,3; Zhou, Wenjuan2; Sun, Yuanxia1,2,3; Zheng, Ping2; Sun, Jibin2; Zhang, Dawei1,2,3 |
| 刊名 | MICROBIAL CELL FACTORIES
 |
| 出版日期 | 2016-04-28 |
| 卷号 | 15 |
| 关键词 | Bacillus subtilis D-Psicose 3-epimerase Fusions Non-classical secretion pathway Localization |
| 英文摘要 | Background: The Gram-positive bacterium Bacillus subtilis has been widely used as a cell factory for the production of proteins due to its generally regarded as safe (GRAS) nature and secretion capability. Of the known secretory pathways in B. subtilis, the majority of proteins are exported from the cytoplasm by Sec pathway, Tat pathway and ABC transporters, etc. However, the production of heterologous proteins by B. subtilis is unfortunately not that straight forward because of the bottlenecks in classical secretion pathways. The aim of this work is to explore a new method for protein production based on non-classical secretion pathway. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Biotechnology & Applied Microbiology |
| 研究领域[WOS] | Biotechnology & Applied Microbiology |
| 关键词[WOS] | ESCHERICHIA-COLI ; SIGNAL PEPTIDE ; EXTRACELLULAR PRODUCTION ; CYTOPLASMIC PROTEINS ; RECOMBINANT PROTEINS ; BACTERIAL PROTEINS ; PRSA LIPOPROTEIN ; ALPHA-AMYLASE ; D-PSICOSE ; EXPRESSION |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000375656400001 |
| 源URL | [http://124.16.173.210/handle/834782/2246]  |
| 专题 | 天津工业生物技术研究所_微生物生理与蛋白质组学 张大伟_期刊论文 |
| 作者单位 | 1.Natl Engn Lab Ind Enzymes, Tianjin 300308, Peoples R China 2.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Tianjin 300308, Peoples R China 3.Chinese Acad Sci, Key Lab Syst Microbial Biotechnol, Tianjin 300308, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Jingqi,Zhao, Liuqun,Fu, Gang,et al. A novel strategy for protein production using non-classical secretion pathway in Bacillus subtilis[J]. MICROBIAL CELL FACTORIES,2016,15. |
| APA | Chen, Jingqi.,Zhao, Liuqun.,Fu, Gang.,Zhou, Wenjuan.,Sun, Yuanxia.,...&Zhang, Dawei.(2016).A novel strategy for protein production using non-classical secretion pathway in Bacillus subtilis.MICROBIAL CELL FACTORIES,15. |
| MLA | Chen, Jingqi,et al."A novel strategy for protein production using non-classical secretion pathway in Bacillus subtilis".MICROBIAL CELL FACTORIES 15(2016). |
入库方式： OAI收割
来源：天津工业生物技术研究所
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