BioSynther: a customized biosynthetic potential explorer
文献类型：期刊论文
| 作者 | Tu, Weizhong1,2; Zhang, Haoran3,4; Liu, Juan3,4; Hu, Qian-Nan1,2,5 |
| 刊名 | BIOINFORMATICS
 |
| 出版日期 | 2016-02-01 |
| 卷号 | 32期号:3页码:472-473 |
| 英文摘要 | Motivation: One of the most promising applications of biosynthetic methods is to produce chemical products of high value from the ready-made chemicals. To explore the biosynthetic potentials of a chemical as a synthesis precursor, biosynthetic databases and related chemoinformatics tools are urgently needed. In the present work, a web-based tool, BioSynther, is developed to explore the biosynthetic potentials of precursor chemicals using BKM-react, Rhea, and more than 50 000 inhouse RxnFinder reactions manually curated. BioSynther allows researchers to explore biosynthetic potentials, through so far known biochemical reactions, step by step interactively, which could be used as a useful tool in metabolic engineering and synthetic biology. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Technology ; Physical Sciences |
| 类目[WOS] | Biochemical Research Methods ; Biotechnology & Applied Microbiology ; Computer Science, Interdisciplinary Applications ; Mathematical & Computational Biology ; Statistics & Probability |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Computer Science ; Mathematical & Computational Biology ; Mathematics |
| 关键词[WOS] | COMPUTATIONAL TOOLS ; METABOLIC PATHWAYS ; BULK CHEMICALS ; DESIGN ; MICROORGANISMS ; BIOFUELS ; BIOLOGY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000370203000026 |
| 源URL | [http://124.16.173.210/handle/834782/2894]  |
| 专题 | 天津工业生物技术研究所_细胞工厂设计研究组 胡黔楠_期刊论文 |
| 作者单位 | 1.Wuhan Univ, Minist Educ, Key Lab Combinatorial Biosynth & Drug Discovery, Wuhan 430071, Peoples R China 2.Wuhan Univ, Sch Pharmaceut Sci, Wuhan 430071, Peoples R China 3.Wuhan Univ, State Key Lab Software Engn, Wuhan 430072, Peoples R China 4.Wuhan Univ, Sch Comp Sci, Wuhan 430072, Peoples R China 5.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Key Lab Syst Microbial Biotechnol, Tianjin, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tu, Weizhong,Zhang, Haoran,Liu, Juan,et al. BioSynther: a customized biosynthetic potential explorer[J]. BIOINFORMATICS,2016,32(3):472-473. |
| APA | Tu, Weizhong,Zhang, Haoran,Liu, Juan,&Hu, Qian-Nan.(2016).BioSynther: a customized biosynthetic potential explorer.BIOINFORMATICS,32(3),472-473. |
| MLA | Tu, Weizhong,et al."BioSynther: a customized biosynthetic potential explorer".BIOINFORMATICS 32.3(2016):472-473. |
入库方式： OAI收割
来源：天津工业生物技术研究所
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