Harnessing cross-species alignment to discover SNPs and generate a draft genome sequence of a bighorn sheep (Ovis canadensis)
文献类型：期刊论文
| 作者 | Miller, Joshua M.1; Moore, Stephen S.2,3; Stothard, Paul3; Liao, Xiaoping4; Coltman, David W.1 |
| 刊名 | BMC GENOMICS
 |
| 出版日期 | 2015-05-20 |
| 卷号 | 16 |
| 关键词 | Cross-species alignment Comparative genomics Domestication |
| 英文摘要 | Background: Whole genome sequences (WGS) have proliferated as sequencing technology continues to improve and costs decline. While many WGS of model or domestic organisms have been produced, a growing number of non-model species are also being sequenced. In the absence of a reference, construction of a genome sequence necessitates de novo assembly which may be beyond the ability of many labs due to the large volumes of raw sequence data and extensive bioinformatics required. In contrast, the presence of a reference WGS allows for alignment which is more tractable than assembly. Recent work has highlighted that the reference need not come from the same species, potentially enabling a wide array of species WGS to be constructed using cross-species alignment. Here we report on the creation a draft WGS from a single bighorn sheep (Ovis canadensis) using alignment to the closely related domestic sheep (Ovis aries). |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Biotechnology & Applied Microbiology ; Genetics & Heredity |
| 研究领域[WOS] | Biotechnology & Applied Microbiology ; Genetics & Heredity |
| 关键词[WOS] | POPULATION GENOMICS ; LINKAGE DISEQUILIBRIUM ; CONSERVATION GENETICS ; SEXUAL SELECTION ; SOLID SEQUENCE ; FIELD GUIDE ; SHORT READS ; HISTORY ; TRAITS ; ANNOTATION |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000354846100002 |
| 源URL | [http://124.16.173.210/handle/834782/2883]  |
| 专题 | 天津工业生物技术研究所_总体研究部_期刊论文 |
| 作者单位 | 1.Univ Alberta, Dept Biol Sci, Edmonton, AB, Canada 2.Univ Queensland, Queensland Alliance Agr & Food Innovat, Ctr Anim Sci, St Lucia, Qld, Australia 3.Univ Alberta, Dept Agr Food & Nutr Sci, Edmonton, AB, Canada 4.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Tianjin, Peoples R China |
| 推荐引用方式 GB/T 7714 | Miller, Joshua M.,Moore, Stephen S.,Stothard, Paul,et al. Harnessing cross-species alignment to discover SNPs and generate a draft genome sequence of a bighorn sheep (Ovis canadensis)[J]. BMC GENOMICS,2015,16. |
| APA | Miller, Joshua M.,Moore, Stephen S.,Stothard, Paul,Liao, Xiaoping,&Coltman, David W..(2015).Harnessing cross-species alignment to discover SNPs and generate a draft genome sequence of a bighorn sheep (Ovis canadensis).BMC GENOMICS,16. |
| MLA | Miller, Joshua M.,et al."Harnessing cross-species alignment to discover SNPs and generate a draft genome sequence of a bighorn sheep (Ovis canadensis)".BMC GENOMICS 16(2015). |
入库方式： OAI收割
来源：天津工业生物技术研究所
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