Facet Energy and Reactivity versus Cytotoxicity: The Surprising Behavior of CdS Nanorods
文献类型：期刊论文
| 作者 | Liu, Lu1; Sun, Meiqing1; Zhang, Haijun1; Yu, Qilin2; Li, Mingchun2; Qi, Yu1; Zhang, Chengdong1; Gao, Guandao1; Yuan, Yingjin3; Zhai, Huanhuan4 |
| 刊名 | NANO LETTERS
 |
| 出版日期 | 2016 |
| 卷号 | 16期号:1页码:688-694 |
| 关键词 | Surface energy crystal facets nanotoxicity CdS nanorods Saccharomyces cerevisiae |
| 英文摘要 | Responsible development of nanotechnology calls for improved understanding of how nanomaterial surface energy and reactivity affect potential toxicity. Here, we challenge the paradigm that cytotoxicity increases with nanoparticle reactivity. Higher-surface-energy {001}-faceted CdS nanorods (CdS-H) were less toxic to Saccharomyces cerevisiae than lower-energy ({101}-faceted) nanorods (CdS-L) of similar morphology, aggregate size, and charge. CdS-H adsorbed to the yeast's cell wall to a greater extent than CdS-L, which decreased endocytosis and cytotoxicity. Higher uptake of CdS-L decreased cell viability and increased endoplasmatic reticulum stress despite lower release of toxic Cd2+ ions. Higher toxicity of CdS-L was confirmed with five different unicellular microorganisms. Overall, higher-energy nanocrystals may exhibit greater propensity to adsorb to or react with biological protective barriers and/or background constituents, which passivates their reactivity and reduces their bioavailability and cytotoxicity. |
| WOS标题词 | Science & Technology ; Physical Sciences ; Technology |
| 类目[WOS] | Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter |
| 研究领域[WOS] | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 关键词[WOS] | ZINC-OXIDE NANOPARTICLES ; CARBON NANOTUBES ; QUANTUM DOTS ; PHOTOCATALYTIC PROPERTIES ; ENGINEERED NANOMATERIALS ; SACCHAROMYCES-CEREVISIAE ; CAENORHABDITIS-ELEGANS ; ANTIBACTERIAL ACTIVITY ; ENDOPLASMIC-RETICULUM ; GOLD NANOPARTICLES |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000368322700105 |
| 源URL | [http://124.16.173.210/handle/834782/2893]  |
| 专题 | 天津工业生物技术研究所_总体研究部_期刊论文 |
| 作者单位 | 1.Nankai Univ, Coll Environm Sci & Engn, Tianjin Key Lab Environm Remediat & Pollut Contro, Tianjin 300071, Peoples R China 2.Nankai Univ, Minist Educ, Coll Life Sci, Key Lab Mol Microbiol & Technol, Tianjin 300071, Peoples R China 3.Tianjin Univ, Key Lab Syst Bioengn, Minist Educ, Tianjin 300072, Peoples R China 4.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Airport Econ Zone, Tianjin 300308, Peoples R China 5.Rice Univ, Dept Civil & Environm Engn, Houston, TX 77005 USA |
| 推荐引用方式 GB/T 7714 | Liu, Lu,Sun, Meiqing,Zhang, Haijun,et al. Facet Energy and Reactivity versus Cytotoxicity: The Surprising Behavior of CdS Nanorods[J]. NANO LETTERS,2016,16(1):688-694. |
| APA | Liu, Lu.,Sun, Meiqing.,Zhang, Haijun.,Yu, Qilin.,Li, Mingchun.,...&Alvarez, Pedro J. J..(2016).Facet Energy and Reactivity versus Cytotoxicity: The Surprising Behavior of CdS Nanorods.NANO LETTERS,16(1),688-694. |
| MLA | Liu, Lu,et al."Facet Energy and Reactivity versus Cytotoxicity: The Surprising Behavior of CdS Nanorods".NANO LETTERS 16.1(2016):688-694. |
入库方式： OAI收割
来源：天津工业生物技术研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。