Separation of antioxidant and -glucosidase inhibitory flavonoids from the aerial parts of Asterothamnus centrali-asiaticus
文献类型：期刊论文
| 作者 | Wang YM(王衍明)1,2; Zhao, Jian-Qiang3; Yang JL(杨军丽)1,2 ; Tao, Yan-Duo3; Mei, Li-Juan3; Shi YP(师彦平)1,2; Shi YP(师彦平)
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| 刊名 | Natural Product Research
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| 出版日期 | 2017 |
| 卷号 | 31期号:12页码:1365-1369 |
| ISSN号 | 1478-6419 |
| 关键词 | Asterothamnus centrali-asiaticus flavonoids antioxidants alpha-glucosidase inhibitors |
| 通讯作者 | 师彦平 |
| 英文摘要 | A new flavonoid, along with 16 known ones, was separated from the aerial parts of Asterothamnus centrali-asiaticus. Their structures were elucidated by extensive spectroscopic methods, including 1D and 2D NMR techniques and HRESIMS. To confirm the structure of the new compound, computational prediction of its 13C chemical shifts was performed. All of the 17 flavonoids were reported from A. centrali-asiaticus for the first time. In addition, all flavonoids were evaluated for their antioxidant and α-glucosidase inhibitory activities. The results showed that 10 of them exhibited antioxidant activity. Meanwhile, four flavonoids displayed α-glucosidase inhibitory effect with IC50 values ranging from 38.9 to 299.7 μM. |
| 学科主题 | 分析化学与药物化学 |
| 资助信息 | the National Nature Science Foundation of China [grant number 21375136];[grant number 21575150];the scientific research project of Central Asia Drug Discovery and Development Centre of Chinese Academy of Sciences [grant number CAM201404];the CAS Pioneer Hundred Talents Program |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000395165600003 |
| 源URL | [http://210.77.64.217/handle/362003/21532]  |
| 专题 | 兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| 通讯作者 | Shi YP(师彦平) |
| 作者单位 | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources CAS, Lanzhou, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou, Peoples R China 3.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang YM,Zhao, Jian-Qiang,Yang JL,et al. Separation of antioxidant and -glucosidase inhibitory flavonoids from the aerial parts of Asterothamnus centrali-asiaticus[J]. Natural Product Research,2017,31(12):1365-1369. |
| APA | Wang YM.,Zhao, Jian-Qiang.,Yang JL.,Tao, Yan-Duo.,Mei, Li-Juan.,...&师彦平.(2017).Separation of antioxidant and -glucosidase inhibitory flavonoids from the aerial parts of Asterothamnus centrali-asiaticus.Natural Product Research,31(12),1365-1369. |
| MLA | Wang YM,et al."Separation of antioxidant and -glucosidase inhibitory flavonoids from the aerial parts of Asterothamnus centrali-asiaticus".Natural Product Research 31.12(2017):1365-1369. |
入库方式： OAI收割
来源：兰州化学物理研究所
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