Silicon surface modification with supported phospholipids bilayer for biosensor based on imaging ellipsometry
文献类型：会议论文
| 作者 | Chen YY(陈艳艳) ; Wang ZH; Liu Y; Liang W; Chang WR; Jin G(靳刚)
|
| 出版日期 | 2008 |
| 会议名称 | 4th European Conference of the International Federation for Medical and Biological Engineering, ECIFMBE 2008 |
| 会议日期 | November 23, 2008 - November 27, 2008 |
| 会议地点 | Antwerp, Belgium |
| 关键词 | Bi-layer Carboxyl groups Covalent immobilization Functionalized Imaging ellipsometry Microfluidic array Phosphatidylethanolamine Phospholipids bilayer Silicon surfaces |
| 中文摘要 | A method is presented for fabricating supported phospholipids bilayer on silicon surface for biosensor based on imaging ellipsometry. The lipid bilayer prepared by covalent immobilization of phosphatidylethanolamine layer on silicon surface followed by adsorption of PEG functionalized phospholipids layer, is highly protein resistant and stable, which can withstand multiple cycles of drying and rehydration, remaining intact in various buffers. Proteins covalently immobilized on the bilayer by the terminal p-nitrophenylcarbonyl or carboxyl group of PEG remain higher bioactivity than that immobilized on silicon surface directly. © 2009 Springer Berlin Heidelberg. |
| 收录类别 | CPCI-S ; EI |
| 会议网址 | http://dx.doi.org/10.1007/978-3-540-89208-3_551 |
| 会议录 | IFMBE Proceedings
 |
| 语种 | 英语 |
| WOS记录号 | WOS:000299998500551 |
| 源URL | [http://dspace.imech.ac.cn/handle/311007/60310]  |
| 专题 | 力学研究所_力学所知识产出(1956-2008) |
| 推荐引用方式 GB/T 7714 | Chen YY,Wang ZH,Liu Y,et al. Silicon surface modification with supported phospholipids bilayer for biosensor based on imaging ellipsometry[C]. 见:4th European Conference of the International Federation for Medical and Biological Engineering, ECIFMBE 2008. Antwerp, Belgium. November 23, 2008 - November 27, 2008.http://dx.doi.org/10.1007/978-3-540-89208-3_551. |
入库方式： OAI收割
来源：力学研究所
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