Hydroxyapatite nanorod-assembled porous hollow polyhedra as drug/protein carriers
文献类型：期刊论文
| 作者 | Yu, Ya-Dong1,2; Zhu, Ying-Jie1,2; Qi, Chao1; Jiang, Ying-Ying1,2; Li, Heng1,2; Wu, Jin1 |
| 刊名 | JOURNAL OF COLLOID AND INTERFACE SCIENCE
 |
| 出版日期 | 2017-06-15 |
| 卷号 | 496页码:416-424 |
| 关键词 | Hydroxyapatite Biomaterials Hydrothermal Drug delivery Protein adsorption |
| 英文摘要 | Hydroxyapatite (HAP) with a porous hollow structure is an ideal biomaterial owing to its excellent biocompatibility and unique architecture. In this study, HAP nanorod-assembled porous hollow polyhedra, consisting of nanorod building blocks, have been successfully prepared at room temperature or under hydrothermal circumstances using a self-sacrificing Ca(OH)(2) template strategy. The hydrothermal treatment (at 180 degrees C for 1 h) can promote the HAP nanorods to be arranged with their axial direction normal to the polyhedron surface. The HAP nanorod-assembled porous hollow polyhedra have been explored for the potential application in drug/protein delivery, using ibuprofen (IBU) as a model drug and hemoglobin (Hb) as a model protein. The experimental results indicate that the HAP nanorod-assembled porous hollow polyhedra have a relatively high drug loading capacity and protein adsorption ability, and sustained drug and protein release. The HAP nanorod-assembled porous hollow polyhedra have promising applications in various biomedical fields such as the drug and protein delivery.(C) 2017 Elsevier Inc. All rights reserved. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Chemistry, Physical |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | ORGANIC PHOSPHORUS SOURCE ; DRUG-DELIVERY ; PROTEIN ADSORPTION ; HYDROTHERMAL SYNTHESIS ; CREATINE-PHOSPHATE ; RAPID SYNTHESIS ; WATER-TREATMENT ; GENE DELIVERY ; MICROSPHERES ; BONE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000398425800045 |
| 源URL | [http://ir.sic.ac.cn/handle/331005/23774]  |
| 专题 | 上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yu, Ya-Dong,Zhu, Ying-Jie,Qi, Chao,et al. Hydroxyapatite nanorod-assembled porous hollow polyhedra as drug/protein carriers[J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE,2017,496:416-424. |
| APA | Yu, Ya-Dong,Zhu, Ying-Jie,Qi, Chao,Jiang, Ying-Ying,Li, Heng,&Wu, Jin.(2017).Hydroxyapatite nanorod-assembled porous hollow polyhedra as drug/protein carriers.JOURNAL OF COLLOID AND INTERFACE SCIENCE,496,416-424. |
| MLA | Yu, Ya-Dong,et al."Hydroxyapatite nanorod-assembled porous hollow polyhedra as drug/protein carriers".JOURNAL OF COLLOID AND INTERFACE SCIENCE 496(2017):416-424. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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