An NBD-based Fluorescent Turn-on Probe for the Detection of Homocysteine over Cysteine and Its Imaging Applications
文献类型：期刊论文
| 作者 | Wang JM(王佳敏)1 ; Shao, Xiangmin2; Wang, Jianhong1; Shao SJ(邵士俊)3,4,5
|
| 刊名 | Chemistry Letters
 |
| 出版日期 | 2017 |
| 卷号 | 46期号:4页码:442-445 |
| 关键词 | Fluorescence probe Bioimaging Thiol-containing molecule |
| ISSN号 | 0366-7022 |
| 通讯作者 | Wang, Jianhong ; 邵士俊 |
| 英文摘要 | An NBD-based fluorescent probe (probe 1) for the detection of Hcy over Cys and GSH based on nucleophilic substitution and Smiles rearrangement reaction was designed and synthesized by the reaction of 4-chloro-7-nitro-2,1,3-benzoxadiazole (NBD-Cl) with 1,4-dihydroxybenzene. The probe displayed many desired properties such as high specificity, appreciable solubility, and desirable response time. In addition, probe 1 has low cytotoxicity and detection of intracellular Hcy can be achieved by cell fluorescence imaging. |
| 学科主题 | 分析化学与药物化学 |
| 收录类别 | SCI |
| 资助信息 | the National Natural Science Foundation of China (Nos. 21275150;21272056;21572239) |
| 语种 | 英语 |
| WOS记录号 | WOS:000396814900007 |
| 源URL | [http://210.77.64.217/handle/362003/21732]  |
| 专题 | 兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| 作者单位 | 1.Henan Univ, Key Lab Nat Med & Immunoengn Henan Prov, Kaifeng 475004, Peoples R China 2.Zhengzhou Univ Ind Technol, Sch Pharm, Zhengzhou 451100, Peoples R China 3.Chinese Acad Sci, Lanzhou Inst Chem Phys, CAS Key Lab Chem NW Plant Resources, Lanzhou 730000, Peoples R China 4.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 5.Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang JM,Shao, Xiangmin,Wang, Jianhong,et al. An NBD-based Fluorescent Turn-on Probe for the Detection of Homocysteine over Cysteine and Its Imaging Applications[J]. Chemistry Letters,2017,46(4):442-445. |
| APA | Wang JM,Shao, Xiangmin,Wang, Jianhong,&Shao SJ.(2017).An NBD-based Fluorescent Turn-on Probe for the Detection of Homocysteine over Cysteine and Its Imaging Applications.Chemistry Letters,46(4),442-445. |
| MLA | Wang JM,et al."An NBD-based Fluorescent Turn-on Probe for the Detection of Homocysteine over Cysteine and Its Imaging Applications".Chemistry Letters 46.4(2017):442-445. |
入库方式： OAI收割
来源：兰州化学物理研究所
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