Capillary zone electrophoresis investigation of the interaction between heparin and granulocyte-colony stimulating factor
文献类型:期刊论文
作者 | Liang, AY; He, XY; Du, YG; Wang, KY; Fung, YS; Lin, BC |
刊名 | electrophoresis
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出版日期 | 2004-03-01 |
卷号 | 25期号:6页码:870-875 |
关键词 | capillary zone electrophoresis granulocyte-colony stimulating factor heparin |
产权排序 | 1;1 |
英文摘要 | the interaction between standard heparin, low-molecular-weight heparin (lmwh), and granulocyte-colony stimulating factor (g-csf) was studied by capillary zone electrophoresis. both qualitative and quantitative characterizations of the heparin-protein binding were determined. the binding constants of the two different groups of heparins with g-csf, calculated from the scatchard plot by regression, were 4.805 x 10(5) m(-1) and 4.579 x 10(5) m(-1), respectively. the two binding constants measured are of the same order of magnitude at 10(5) m(-1), indicating that lmwh contains most of the functional groups bound to g-csf by standard heparin. |
WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
类目[WOS] | biochemical research methods ; chemistry, analytical |
研究领域[WOS] | biochemistry & molecular biology ; chemistry |
关键词[WOS] | fibroblast-growth-factor ; human serum-albumin ; amyloid-p component ; antithrombin-binding ; drug enantiomers ; domain ; dna ; peptides ; sequence ; site |
收录类别 | SCI |
原文出处 | true |
语种 | 英语 |
WOS记录号 | WOS:000220347900014 |
公开日期 | 2010-11-30 |
源URL | [http://159.226.238.44/handle/321008/81101] ![]() |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Shanghai Acad Life Sci, Inst Biochem & Cell Biol, Shanghai, Peoples R China 3.Univ Hong Kong, Dept Chem, Hong Kong, Hong Kong, Peoples R China |
推荐引用方式 GB/T 7714 | Liang, AY,He, XY,Du, YG,et al. Capillary zone electrophoresis investigation of the interaction between heparin and granulocyte-colony stimulating factor[J]. electrophoresis,2004,25(6):870-875. |
APA | Liang, AY,He, XY,Du, YG,Wang, KY,Fung, YS,&Lin, BC.(2004).Capillary zone electrophoresis investigation of the interaction between heparin and granulocyte-colony stimulating factor.electrophoresis,25(6),870-875. |
MLA | Liang, AY,et al."Capillary zone electrophoresis investigation of the interaction between heparin and granulocyte-colony stimulating factor".electrophoresis 25.6(2004):870-875. |
入库方式: OAI收割
来源:大连化学物理研究所
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