中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Capillary zone electrophoresis investigation of the interaction between heparin and granulocyte-colony stimulating factor

文献类型:期刊论文

作者Liang, AY; He, XY; Du, YG; Wang, KY; Fung, YS; Lin, BC
刊名electrophoresis
出版日期2004-03-01
卷号25期号:6页码:870-875
关键词capillary zone electrophoresis granulocyte-colony stimulating factor heparin
产权排序1;1
英文摘要the interaction between standard heparin, low-molecular-weight heparin (lmwh), and granulocyte-colony stimulating factor (g-csf) was studied by capillary zone electrophoresis. both qualitative and quantitative characterizations of the heparin-protein binding were determined. the binding constants of the two different groups of heparins with g-csf, calculated from the scatchard plot by regression, were 4.805 x 10(5) m(-1) and 4.579 x 10(5) m(-1), respectively. the two binding constants measured are of the same order of magnitude at 10(5) m(-1), indicating that lmwh contains most of the functional groups bound to g-csf by standard heparin.
WOS标题词science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]biochemical research methods ; chemistry, analytical
研究领域[WOS]biochemistry & molecular biology ; chemistry
关键词[WOS]fibroblast-growth-factor ; human serum-albumin ; amyloid-p component ; antithrombin-binding ; drug enantiomers ; domain ; dna ; peptides ; sequence ; site
收录类别SCI
原文出处true
语种英语
WOS记录号WOS:000220347900014
公开日期2010-11-30
源URL[http://159.226.238.44/handle/321008/81101]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Shanghai Acad Life Sci, Inst Biochem & Cell Biol, Shanghai, Peoples R China
3.Univ Hong Kong, Dept Chem, Hong Kong, Hong Kong, Peoples R China
推荐引用方式
GB/T 7714
Liang, AY,He, XY,Du, YG,et al. Capillary zone electrophoresis investigation of the interaction between heparin and granulocyte-colony stimulating factor[J]. electrophoresis,2004,25(6):870-875.
APA Liang, AY,He, XY,Du, YG,Wang, KY,Fung, YS,&Lin, BC.(2004).Capillary zone electrophoresis investigation of the interaction between heparin and granulocyte-colony stimulating factor.electrophoresis,25(6),870-875.
MLA Liang, AY,et al."Capillary zone electrophoresis investigation of the interaction between heparin and granulocyte-colony stimulating factor".electrophoresis 25.6(2004):870-875.

入库方式: OAI收割

来源:大连化学物理研究所

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