Discrimination of Type 2 diabetic patients from healthy controls by using metabonomics method based on their serum fatty acid profiles
文献类型：期刊论文
| 作者 | Yang, J; Xu, GW; Hong, QF; Liebich, HM; Lutz, K; Schmulling, RM; Wahl, HG |
| 刊名 | journal of chromatography b-analytical technologies in the biomedical and life sciences
 |
| 出版日期 | 2004-12-25 |
| 卷号 | 813期号:1-2页码:53-58 |
| 关键词 | pattern recognition diabetes mellitus fatty acid profiles linear discriminant analysis artificial neural networks metabonomics |
| 产权排序 | 1;1 |
| 英文摘要 | metabonomics, the study of metabolites and their roles in various disease states, is a novel methodology arising from the post-genomics era. this methodology has been applied in many fields, including work in cardiovascular research and drug toxicology. in this study, metabonomics method was employed to the diagnosis of type 2 diabetes mellitus (dm2) based on serum lipid metabolites. the results suggested that serum fatty acid profiles determined by capillary gas chromatography combined with pattern recognition analysis of the data might provide an effective approach to the discrimination of type 2 diabetic patients from healthy controls. and the applications of pattern recognition methods have improved the sensitivity and specificity greatly. (c) 2004 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | functional genomics ; neural networks ; mellitus ; lipids |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000225413200005 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/81603]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&D Ctr, Dalian 116011, Peoples R China 2.Univ Tubingen, Med Klin, Zent Lab, D-72076 Tubingen, Germany 3.Klinikum FUlda, Inst Lab Med, D-36043 Fulda, Germany |
| 推荐引用方式 GB/T 7714 | Yang, J,Xu, GW,Hong, QF,et al. Discrimination of Type 2 diabetic patients from healthy controls by using metabonomics method based on their serum fatty acid profiles[J]. journal of chromatography b-analytical technologies in the biomedical and life sciences,2004,813(1-2):53-58. |
| APA | Yang, J.,Xu, GW.,Hong, QF.,Liebich, HM.,Lutz, K.,...&Wahl, HG.(2004).Discrimination of Type 2 diabetic patients from healthy controls by using metabonomics method based on their serum fatty acid profiles.journal of chromatography b-analytical technologies in the biomedical and life sciences,813(1-2),53-58. |
| MLA | Yang, J,et al."Discrimination of Type 2 diabetic patients from healthy controls by using metabonomics method based on their serum fatty acid profiles".journal of chromatography b-analytical technologies in the biomedical and life sciences 813.1-2(2004):53-58. |
入库方式： OAI收割
来源：大连化学物理研究所
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