Swelling behaviour of alginate-chitosan microcapsules prepared by external gelation or internal gelation technology
文献类型：期刊论文
| 作者 | Liu, XD; Xue, WM; Liu, Q; Yu, WT; Fu, YL; Xiong, X; Ma, XJ; Yuan, Q |
| 刊名 | carbohydrate polymers
 |
| 出版日期 | 2004-07-15 |
| 卷号 | 56期号:4页码:459-464 |
| 关键词 | swelling behaviour alginate-chitosan microcapsule external gelation internal gelation |
| 产权排序 | 1;1 |
| 英文摘要 | swelling behaviour is one of the important properties for microcapsules made by hydrogels, which always affects the diffusion and release of drugs when the microcapsules are applied in drug delivery systems. in this paper, alginate-chitosan microcapsules were prepared by different technologies called external or internal gelation process respectively. with the volume swelling degree (s-w) as an index, the effect of properties of chitosan on the swelling behaviour of both microcapsules was investigated. it was demonstrated that the microcapsules with low molecular weight and high concentration of chitosan gave rise to low s-w. considering the need of maintaining drug activity and drug loading, neutral ph and short gelation time were favorable. it was also noticed that s-w of internal gelation microcapsules was lower than that of external gelation microcapsules, which was interpreted by the structure analysis of internal or external gelation ca-alginate beads with the aid of confocal laser scanning microscope. (c) 2004 elsevier ltd. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, applied ; chemistry, organic ; polymer science |
| 研究领域[WOS] | chemistry ; polymer science |
| 关键词[WOS] | delivery ; beads ; release |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000222747100008 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/81965]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Lab Biomed Mat Engn, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, XD,Xue, WM,Liu, Q,et al. Swelling behaviour of alginate-chitosan microcapsules prepared by external gelation or internal gelation technology[J]. carbohydrate polymers,2004,56(4):459-464. |
| APA | Liu, XD.,Xue, WM.,Liu, Q.,Yu, WT.,Fu, YL.,...&Yuan, Q.(2004).Swelling behaviour of alginate-chitosan microcapsules prepared by external gelation or internal gelation technology.carbohydrate polymers,56(4),459-464. |
| MLA | Liu, XD,et al."Swelling behaviour of alginate-chitosan microcapsules prepared by external gelation or internal gelation technology".carbohydrate polymers 56.4(2004):459-464. |
入库方式： OAI收割
来源：大连化学物理研究所
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