Application of uniform design and genetic algorithm in optimization of reversed-phase chromatographic separation
文献类型：期刊论文
| 作者 | Chen, XG; Li, X; Kong, L; Ni, JY; Zhao, RH; Zou, HF |
| 刊名 | chemometrics and intelligent laboratory systems
 |
| 出版日期 | 2003-08-28 |
| 卷号 | 67期号:2页码:157-166 |
| 关键词 | genetic algorithm uniform design optimization reversed-phase chromatographic separation |
| 产权排序 | 1;1 |
| 英文摘要 | an optimization method based on uniform design in conjunction with genetic algorithm is described. according to the proposed method, the uniform design technique was applied to the design of starting experiments, which can reduce the number of experiments compared with traditional simultaneous methods, such as simplex. and genetic algorithm was used in optimization procedure, which can improve the rapidity of optimal procedure. the hierarchical chromatographic response function was modified to evaluate the separation equality of a chromatogram. an iterative procedure was adopted to search for the optimal condition to improve the accuracy of predicted retention and the quality of the chromatogram. the optimization procedure was tested in optimization of the chromatographic separation of 11 alkaloids in reversed-phase ion pair chromatography and satisfactory optimal result was obtained. (c) 2003 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; technology ; physical sciences |
| 类目[WOS] | automation & control systems ; chemistry, analytical ; computer science, artificial intelligence ; instruments & instrumentation ; mathematics, interdisciplinary applications ; statistics & probability |
| 研究领域[WOS] | automation & control systems ; chemistry ; computer science ; instruments & instrumentation ; mathematics |
| 关键词[WOS] | performance liquid-chromatography ; identification ; model |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000185059400006 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/82395]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116011, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, XG,Li, X,Kong, L,et al. Application of uniform design and genetic algorithm in optimization of reversed-phase chromatographic separation[J]. chemometrics and intelligent laboratory systems,2003,67(2):157-166. |
| APA | Chen, XG,Li, X,Kong, L,Ni, JY,Zhao, RH,&Zou, HF.(2003).Application of uniform design and genetic algorithm in optimization of reversed-phase chromatographic separation.chemometrics and intelligent laboratory systems,67(2),157-166. |
| MLA | Chen, XG,et al."Application of uniform design and genetic algorithm in optimization of reversed-phase chromatographic separation".chemometrics and intelligent laboratory systems 67.2(2003):157-166. |
入库方式： OAI收割
来源：大连化学物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。